学龄儿童碘营养状况与甲状腺结节患病关系  

Iodine nutritional status and the thyroid nodules prevalence of school-age children

作　　者：丁钢强[1] 莫哲[1] 楼晓明[1] 朱文明[1] 周金水[1] 毛光明[1] 杨章萍[2] 

机构地区：[1]浙江省疾病预防控制中心,杭州310051 [2]杭州市疾病预防控制中心

出　　处：《中国学校卫生》2012年第11期1341-1343,共3页Chinese Journal of School Health

基　　金：浙江省科技厅重大专项(2009C03010-1)

摘　　要：目的了解浙江省学龄儿童碘营养状况及甲状腺结节患病水平及两者的关系,为碘缺乏病防治工作提供科学依据。方法整群随机抽取浙江省2个县区8～10岁学龄儿童共689名进行甲状腺B超检查,同时采集尿液进行尿碘检测。结果浙江省8～10岁学龄儿童甲状腺结节患病率为6.96%;学龄儿童尿碘中位数为180.50μg/L;0～99μg/L组学龄儿童甲状腺结节患病率较高,为8.70%,100～199μg/L组学龄儿童甲状腺结节患病率次之,为5.49%,200～299μg/L组学龄儿童甲状腺结节患病率最高,为9.43%,尿碘水平处于300μg/L以上学龄儿童甲状腺结节患病率最低,为5.16%,差异无统计学意义(χ2=3.71,P>0.05);检出有结节组学龄儿童尿碘中位数为192.68μg/L,而无结节组学龄儿童尿碘中位数为179.50μg/L,差异也无统计学意义(Z=0.77,P>0.05)。结论学龄儿童碘营养状况良好,碘营养水平与甲状腺结节患病水平无相关关系。碘营养水平处于WHO提出的适宜范围内时,甲状腺结节患病率处于较低水平。Objective To evaluate the level of iodine nutrition and the prevalence of the thyroid nodules of school-age children in Zhejiang to explore an scientific basis for the prevention and conformity of iodine deficiency disorders. Methods A cluster sampling method was applied in 11 prefecture-level cities in Zhejiang Province to select 689 children aged 8 - 10 to examine thyroid by B ultrasound, collecting urine to test. Results The thyroid nodules prevalence and the median urinary iodine of school-age children in Zhejiang was respectively 6.96% and 180.50 /.Lg/L. On the other hand, the different urinary iodine levels groups of thyroid nodules prevalence ranked in order as ≥300μg/L, 100- 199 μg/L, 0- 99 μg/L, and 200- 299 μg/L groups, which was respectively 5.16%, 5.49% , 8.70% and 9.43%, but there is no significant difference in four groups（x2 =3.71 ,P 〉0.05 } ; the median urinary iodine of school-age children in detected nodules group was 192.68 μg/L, which was not more than that in no-de- tected nodules group（ 179.50 μg/L,Z = 0.77,P 〉 0.05}. Conclusion The school-aged children in Zhejiang Province show a good iodine nutritional status, there was no relationship between iodine nutritional level and the prevalence of thyroid nodules, when the iodine nutritional level is in the appropriate range which WHO proposed, the thyroid nodule prevalence is at a low level.

关 键 词：碘 营养状况 甲状腺结节 学生 

分 类 号：R153.2[医药卫生—营养与食品卫生学] R581.3[医药卫生—公共卫生与预防医学]