河南省兰考县农村地区功能性肠病的流行病学调查  

An epidemiological study on Functional Bowel Disorders in Rural Areas of Lankao County in Henan Province

作　　者：王利营[1,2] 杨云生[1] 曹晓鹏[3] 彭丽华[1] 蔡赐河[4] 蔡顺天[1] 张雷[5] 

机构地区：[1]解放军总医院消化内科,北京100853 [2]解放军第二炮兵总医院胃食管反流病中心,北京100088 [3]解放军总医院第一附属医院消化内科,北京100037 [4]北京大学公共卫生学院,北京100083 [5]河南省红十字血液中心,河南郑州450053

出　　处：《中国临床医学》2012年第5期485-487,共3页Chinese Journal of Clinical Medicine

基　　金：全军"十一五"科技攻关项目(编号:06G113)

摘　　要：目的:调查河南省兰考县农村地区功能性肠病(functional bowel disorders,FBD)流行病学状况。方法:采用普查方法,对该地区6个村庄全部进行入户问卷调查,按照罗马III功能性胃肠病诊断标准统计FBD患病率,并按照性别、年龄、体质量指数和生活习惯等分组,进行相关危险因素分析。结果:实际共调查3 032例,其中男性1531例,女性1501例;年龄18～109岁。共检出FBD137例(4.52%),女性FBD患病率(5.13%)高于男性(3.92%),但两者差异无统计学意义(P=0.108);男性肠易激综合征(irritable bowel syndrome,IBS)患病率显著低于女性(P<0.05);FBD患病率随年龄增长而升高,60岁以上组达高峰(8.50%,P<0.001),高龄是IBS、功能性腹泻的危险因素;功能性腹胀、IBS及FBD患病率均以消瘦组最高(P<0.05);较少规律进食与FBD有关,较少规律进食、较多进食生冷或辛辣食物是非特异性FBD的危险因素(P<0.05);多元回归分析发现高龄、焦虑和抑郁是FBD的危险因素。结论:河南省兰考县农村地区FBD患病率较低,年龄、不良生活方式是FBD的危险因素,FBD多伴焦虑、抑郁倾向。Objective：To investigate the prevalence of functional bowel disorders （FBD） in the population of the countryside of Lankao county in Henan province. Methods： A census was carried out in 6 villages of the area, using the Rome III criteria to assess the prevalence of FBD and to analyze their related risk factors. Results： A total of 3032 residents （1531 males, 1501 fe males） were investigated. Their age varied from 18 years to 109 years. Of the residents surveyed, 137（4.52 %） were diagnosed with FBD. The prevalence of FBD in females （5. 13%） was higher than that in males （3. 92%）, but the difference was not significant （P = 0. 108）. However, the prevalence of irritable bowel syndrome （IBS） in males was significantly lower than that in females （P〈0.05）. The rate of FBD increased with age, reaching the peak of 8.50% at the age of more than 60 years （P〈 0. 001）, while advanced age was one of the risk factors of IBS and functional diarrhea. The prevalence rates of functional diar rhea, IBS and FBD in underweight group were obviously higher than those in other groups （P〈0.05）. The risk factors of unspecified FBD included irregular diet, eating omophagia, cold drinking and often eating pungent food （P〈0.05）, while FBD was only related with irregular diet. Logistic multiple regression analysis showed that the risk factors of FBD included advanced age, anxiety and depression （P〈0.05）. Conclusions： The prevalence rate of FBD in this area is low. Age, unhealthy life style are the risk factors for FBD. The psychologic obstacles such as anxiety and depression are also correlated with FBD.

关 键 词：功能性肠病 罗马III 流行病学 

分 类 号：R574[医药卫生—消化系统]