Growth-Promoting Effects of Liposome-Encapsulated Porcine Somatotropin in Mice  

作　　者：ZHOU Jun YANG Chun-hua FANG Xi-xiu WANG Dong-mei QI Fu-gang WANG Quan 

机构地区：[1]Animal Veterinary Medicine College, Yangzhou University, Yangzhou 225009, China [2]Feed Research Institute, Jiangsu Animal Husbandry & Veterinary College, Taizhou 225300, China [3]Animal Husbandry Bureau of Kenli County, Dongying 257500, China

出　　处：《Animal Husbandry and Feed Science》2011年第2期8-9,共2页动物与饲料科学（英文版）

摘　　要：[ Objective] To study growth-promoting effects of liposome-encapsulated porcine somatotropin （pST） and its sustained-release effects in mice. [ Method] The mice were randomly divided into experimental groups and control group. The mice in the experimental groups were respective- ly administrated with pST and liposome-encapsulated pST via intraperitoneal injection, and those in the control group were administrated with saline. They were weighed on Day 7, 14 and 28, and the growth rate was calculated. [ Result] The growth of mice had significant difference between the experiment groups and control group （P 〈 0.05）, which indicated that the pST and liposome-encapsulated pST had growth-promoting effects in mice, and the liposome-encapsulated pST had sustained-release effects. [Condusion] The liposome-encapsulated pST can promote the growth of animal and its sustained-release peried is 7 d.[Objective] To study growth-promoting effects of liposome-encapsulated porcine somatotropin (pST) and its sustained-release effects in mice. [Method] The mice were randomly divided into experimental groups and control group. The mice in the experimental groups were respectively administrated with pST and liposome-encapsulated pST via intraperitoneal injection, and those in the control group were administrated with saline. They were weighed on Day 7, 14 and 28, and the growth rate was calculated. [Result] The growth of mice had significant difference between the experiment groups and control group (P < 0.05), which indicated that the pST and liposome-encapsulated pST had growth-promoting effects in mice, and the liposome-encapsulated pST had sustained-release effects. [Conclusion] The liposome-encapsulated pST can promote the growth of animal and its sustained-release period is 7 d.

关 键 词：Porcine somatotropin LIPOSOME Sustained-release effects MICE 

分 类 号：S828[农业科学—畜牧学] Q575.11[农业科学—畜牧兽医]