对甲氧基肉桂酸异辛酯的高效合成研究  

Study on High Efficient Synthesis of Octyl 4-Methoxy Cinnamate

作　　者：林栋[1] 杨奇超[2] 王玉芳[1] 张明杰[1] 

机构地区：[1]天津大学理学院化学系,天津300072 [2]南阳师范学院化学与制药工程学院,河南南阳473061

出　　处：《化学与生物工程》2012年第11期47-49,共3页Chemistry & Bioengineering

摘　　要：采用钯炭催化对溴苯甲醚与丙烯酸异辛酯进行Heck反应合成了对甲氧基肉桂酸异辛酯,产率达99.0%,催化剂回收使用3次,活性无明显损失;反应副产物溴化钠可用于制备对溴苯甲醚。给出了一种高效、经济的对甲氧基肉桂酸异辛酯的合成方法。Oetyl 4-methoxy einnamate was synthesized with a yield of 99.0% through Heek reaction of 4- bromoanisole and isooetyl acrylate catalyzed by Pd/C. The catalyst could be reused for three times without ob- vious activity loss,and the reaction byproduct, NaBr, could be utilized to prepare 4-bromoanisole. An economical and efficient way for synthesis of oetyl 4-methoxy einnamate was given.

关 键 词：对甲氧基肉桂酸异辛酯 HECK反应 钯炭催化剂 

分 类 号：TQ225.241[化学工程—有机化工]