失眠及其相关精神因素对女性肠易激综合征患者的影响  

Influence of insomnia and insomnia-related psychological factors on symptoms of female patients with irritable bowel syndrome

作　　者：杨微微[1] 汤玉蓉[1] 徐新寓[1] 王一琳[1] 林琳[1] 

机构地区：[1]南京医科大学第一附属医院消化科,江苏省南京市210029

出　　处：《世界华人消化杂志》2012年第29期2840-2844,共5页World Chinese Journal of Digestology

基　　金：国家自然科学基金资助项目;No.30971354;江苏省国际科技合作计划基金资助项目;No.BZ2011044~~

摘　　要：目的:探讨失眠和失眠相关精神因素对女性肠易激综合征(irritable bowel syndrome,IBS)患者症状的影响.方法:收集2009-01/10就诊于南京医科大学第一附属医院消化科门诊的成年女性IBS患者245例,对其进行问卷调查:一般人口学资料、症状问卷、阿森斯失眠量表(athens insomnia scale,AIS)、焦虑自评量表(self-rating anxiety scale,SAS)和抑郁自评量表(selfrating depression scale,SDS).根据AIS评分将IBS患者分为失眠组和非失眠组,分别分析失眠对IBS典型症状、躯体症状、精神症状的影响及相关精神因素与IBS典型症状的关系.结果:(1)女性IBS患者中,失眠组典型症状的严重程度及每次发作的持续时间均高于非失眠组(P<0.05),而两组间的发作频率则无差异;(2)女性IBS患者失眠组躯体症状的发生率显著高于非失眠组(P<0.01);(3)失眠组女性IBS患者的SAS、SDS以及剔除睡眠相关条目后的SAS'、SDS'评分均显著高于非失眠组(P<0.01);(4)女性IBS患者典型症状的严重程度、发作频率及每次发作的持续时间均与SAS、SDS评分呈正相关(P<0.05).结论:失眠和失眠相关的焦虑、抑郁精神因素可加重女性IBS患者症状.AIM： To investigate the influence of insomnia and insomnia-related psychological factors on the symptoms of female patients with irritable bowel syndrome （IBS）.METHODS： Two hundred and forty-five adult female outpatients with IBS who were treated at the Department of Gastroenterology of the First Affiliated Hospital of Nanjing Medical Univer- sity were included in this study. A questionnaire survey was conducted using a demographic information questionnaire, a symptom question- naire, athens insomnia scale （AIS）, self-ratinganxiety scale （SAS）, and self-rating depression scale （SDS）. According to AIS scores, female patients with IBS were divided into insomnia group and non-insomnia group. The influence of insomnia on typical symptoms, somatic symp- toms and psychological symptoms of IBS, and the relationship between psychological factors and IBS were analyzed.RESULTS： The insomnia and non-insomnia groups differed significantly in their rating of ab- dominal pain/discomfort in terms of severity and duration （P 〈 0.05）, but there was no difference in attack frequency between the two groups. The in- cidence of somatic symptoms, scores of SAS and SDS, and scores of SAS＇ and SDS＇ （sleep-related entries were removed） were all significantly high- er in the insomnia group than in the non-insom- nia group （all P 〈 0.01）. Severity, attack frequency and duration of abdominal pain/discomfort were all positively correlated with SAS and SDS scores （all P 〈 0.05）.CONCLUSION： Insomnia and insomnia-related psychological factors （anxiety, depression） can aggravate the symptoms of female patients with IBS.

关 键 词：肠易激综合征 失眠 精神因素 症状 女性 

分 类 号：R574[医药卫生—消化系统]