高原地区MS血清某些微量元素的含量变化及其意义探讨  

The serum concentration of five kinds of trace element in patients with MD at plateau area and its significance.

作　　者：杨泽洲[1] 汪如源[2] 耿排力[1] 毛辉青[1] 赵秀丽[2] 邵嘉会[1] 陆东明[1] 靳国恩[1] 

机构地区：[1]青海医学院,青海西宁810001 [2]青海医学院附属医院神经内科,青海西宁810001

出　　处：《中风与神经疾病杂志》2000年第3期155-156,共2页Journal of Apoplexy and Nervous Diseases

基　　金：青海省科委资助课题!( 96-5 -2 0 4)

摘　　要：目的　探讨高原环境下多发性硬化 (MS)血清某些微量元素含量的变化与发病的相关性。方法　以电感耦合等离子体发射光谱法测定 19例 MS患者血清 Zn、Cu、Fe、Mn、Al等 5种微量元素水平。结果　 MS患者血清 Mn、Al水平显著高于正常对照组 ,而 Cu含量则较低。 Zn和 Fe无明显变化。结论　微量元素的改变可能与 MS的发病机制有一定联系。Objective To investigate the changes of serum concentration of some kinds of trace elements in patients with multiple sclerosis (MS) under the condition of plateau environment and the relationship with the pathogenesis. Methods Five kinds of trace elements included Zn,Cu,Fe,Mn and Al were detected by Inductance Coupling Palsma Emission Spectrum in 19 cases of patients with MS. Results The concentration of serum Mn and Al were significantly higher and the level of Cu was lower than that of control group and there were no obvious changes in Zn and Fe concentration. Conculsion It is considered that the changes of some trace element level may closely related with the pathogenesis of MS.

关 键 词：MS 微量元素 多发性硬化症 高原地区 

分 类 号：R744.510.2[医药卫生—神经病学与精神病学]