N-Methylpyridinium tosylate catalyzed green and efficient synthesis of some novel 2,4-disubstituted thiazoles and 4-thiazolidinones  

作　　者：Deepika Gautam Poonam Gautam R.P.Chaudhary 

机构地区：[1]Department of Chemistry,Sant Longowal Institute of Engineering&Technology,Longowal,Sangrur,Punjab 148106,India

出　　处：《Chinese Chemical Letters》2012年第11期1221-1224,共4页中国化学快报（英文版）

摘　　要：A convenient solvent less cyclocondensation from thiosemicarbazone of benzofuranone and chloroacetic acid using an ionic liquid, N-methylpyridinium tosylate for obtaining novel 4-thiazolidinones in excellent yields is reported. Also, the green expedient synthesis of new 2,4-disubstituted thiazoles under grinding condition from phenacyl bromides and thiosemicarbazide derivatives in quantitative yields is reported.A convenient solvent less cyclocondensation from thiosemicarbazone of benzofuranone and chloroacetic acid using an ionic liquid, N-methylpyridinium tosylate for obtaining novel 4-thiazolidinones in excellent yields is reported. Also, the green expedient synthesis of new 2,4-disubstituted thiazoles under grinding condition from phenacyl bromides and thiosemicarbazide derivatives in quantitative yields is reported.

关 键 词：4-Thiazolidinones THIAZOLES Grinding Ionic liquid CYCLOCONDENSATION THIOSEMICARBAZONES 

分 类 号：O626.25[理学—有机化学]