肾结石合并肾盂鳞状细胞癌2例临床分析合并文献复习  

Kidney Stones Merge Pelvis Squamous Cell Carcinoma:Clinical Analysis and Literature

作　　者：谭公祥[1] 余明主[1] 熊海云[1] 

机构地区：[1]中国人民解放军第94医院泌尿外科,330002

出　　处：《实用癌症杂志》2012年第6期643-644,648,共3页The Practical Journal of Cancer

摘　　要：目的探讨肾结石合并肾盂鳞状细胞癌的发生机理、诊断、鉴别诊断及治疗方法。方法对1例术前诊断为右肾结石合并肾肿瘤患者行根治性右肾切除术;另1例左肾结石伴重度积水合并感染的患者行左肾切除术,术中冷冻切片检查提示为恶性肿瘤,遂扩大手术切除范围,行根治性肾切除+输尿管部分切除术。结果 2例患者病理诊断结果均为肾盂鳞状细胞癌,1例术后6个月死于全身功能衰竭,另1例术后随访至今(20个月)无复发。结论肾结石合并肾盂鳞状细胞癌恶性程度高、早期诊断较难,尿路造影及CT等检查结果有助于明确诊断,治疗方法以根治性肾切除术为主。Objective To investigate the renal pelvis squamous cell carcinoma of the pathogenesis,diagnosis,differential diagnosis and treatment method.Methods 1 case of preoperative diagnosis of right renal calculus complicated with renal tumor patients underwent radical right nephrectomy,another case of left kidney stone with severe hydronephrosis complicated with infection in patients underwent left nephrectomy,intraoperative frozen section examination showed malignant tumor,and expand the operation extent of resection,radical nephrectomy plus line ureteral resection operation.Results 2 cases of patients with pathological diagnosis was squamous cell carcinoma of renal pelvis,1 case died 6 months due to postoperatively systemic failure,1 case was followed up till now（20 months） without recurrence.Conclusion Renal calculi complicated with squamous cell carcinoma of the renal pelvis has high degree of malignancy,and early diagnosis is difficult.Urography and CT findings help clarify the diagnosis,major therapeutic approaches are radical nephrectomy.

关 键 词：肾结石 鳞状细胞癌 

分 类 号：R737.11[医药卫生—肿瘤]