复苏后多器官功能障碍综合征123例临床分析  

Clinical study on 123 patients with CPR-MODS

作　　者：王超[1] 胡岚[1] 黄光伟[1] 石秋萍[1] 王红[1] 张淑文[1] 

机构地区：[1]首都医科大学附属北京友谊医院感染内科,北京100050

出　　处：《临床和实验医学杂志》2012年第24期1985-1987,共3页Journal of Clinical and Experimental Medicine

摘　　要：目的探讨复苏后多器官功能障碍综合征(PR-MODS)的临床特点。方法采用回顾性、队列研究。对2003～2007年11个省市、36家三级医院的1 087例MODS中123例PR-MODS病例进行临床分析。结果 PR-MODS组(n=123)与非PR-MODS组(n=964)比较,两者的APACHE II分值分别为(28.4+9.7)分以及(23.7+9.7)分(t=4.954,P=0.000),两者的机械通气天数分别为(11.7+16.0)d和(7.7+11.2)d(t=2.611,P=0.010),两者的住院死亡率分别为71.5%(88/123)和57.1%(550/964)(Pearsonχ2=9.448,P=0.002),两者的血液净化天数分别为2.1+6.1 d和2.2+5.6 d(t=-0.151,P=0.88),两者的住ICU天数分别为14.8+17.5 d和12.8+16.1 d(t=1.178,P=0.241),两者的住院天数分别为25.9+34.6 d和27.6+41.4 d(t=-0.505,P=0.614)。结论 PR-MODS组较非PR-MODS组病情更重、机械通气时间更长、住院病死率更高。Objective To explore the clinical characteristics of multiple organ dysfunction syndrome after cardiopulmonary resuscitation following cardiac arrest （ PR - MODS）. Methods Clinical data of 123 cases of PR - MODS in 1087 cases of MODS were retrospectively analyzed for cohort study. Results In comparison with MODS group after cardiopulmonary resuscitation and MODS group without eardiopulmonary resuscitation, the APACHE II scores were 28.4 ＋ 9.7 and 23.7 ＋ 9.7 respectively （ t = 4. 954, P = 0.000 ）, the duration of mechanical ventilation in these two groups were 11.7 ＋ 16.0 d and 7.7 ＋11.2 d respectively（ t =2.611, P =0.010） ,the mortality of hospital causes was 71.5% （88/123） and 57.1% （550/964） respectively （Pear- son X2 = 9.448, P = 0.002）. The duration for hemodialysis was 2.1 ＋ 6. 1 d and 2. 2 ＋ 5.6 d respectively （ t = - O. 151, P = 0. 88）. The days for ICU stay were 14. 8 ＋ 17.5 d and 12.8 ＋ 16.1 d respectively （ t = 1.178, P = 0. 241 ）, The duration of hospitalization was 25.9 ＋ 34.6 d and 27.6 ＋ 41.4 d respectively （ t = -0.505, P = 0.614）. Conclusion The conditions of patients in MODS group after eardiopulmonary resuseitation are more severe than these of MODS group without eardiopulmonary resuscitation, the duration for mechanical ventilation in former group is longer than that of the latter, and the hospital mortality of the former is higher than the latter one.

关 键 词：心肺复苏 多器官功能障碍综合征 临床特点 

分 类 号：R459.7[医药卫生—急诊医学]