基于多孔粗糙金纳米管阵列电极直接电化学测定抗坏血酸和尿酸  

Direct electrochemical determination of ascorbic acid and uric acid on a rough and porous wall gold nanotube arrays electrode

作　　者：杨光明[1] 

机构地区：[1]保山学院资源环境学院,云南保山678000

出　　处：《保山学院学报》2012年第5期6-11,共6页JOURNAL OF BAOSHAN UNIVERSITY

基　　金：保山学院自然科学基金项目(项目编号:11B005K)

摘　　要：利用循环伏安法(CV)和模板(阳极氧化铝模板(AAO),制备出多孔粗糙金纳米管,壳聚糖将(AAO制备所得)其固定在玻碳电极上,然后将模板溶解,制得金纳米管修饰的传感器,并将其用于抗坏血酸(AA)和尿酸(UA)的直接电化学测定。利用电子扫描电镜(SEM)分析了金纳米管的微观形貌,通过微分差示脉冲伏安(DPV)和循环伏安法考察了抗坏血酸和尿酸在修饰电极上的电化学行为。结果表明,该传感器检测抗坏血酸和尿酸的线性范围分别为1.02×10-7～5.23×10-4mol·L-1和1.43×10-7～4.64×10-4mol·L-1,检测下限分别为1.12×10-8mol·L-1和2.24×10-8mol·L-1。该传感器具有稳定性好,制作简单,使用寿命长等特点,为实际样品中抗坏血酸和尿酸的测定提供了一种新的简便手段。Gold nanotube arrays of rough and porous wall has been synthesized by direct electrodeposition with cyclic voltammetry utilizing anodic aluminum oxide template （AAO）. The morphological characterizations of the gold nanotube arrays have been investigated by scanning electron microscopy （SEM）. A simultaneous determination of ascorbic acid （AA） and uric acid （UA） by differential pulse voltammetry （DPV） was constructed by attaching gold nanotube arrays onto the surface of a glassy carbon electrode （GCE）. The electrochemical behavior of AA and UA at this modified electrode has been studied by CV and DPV. The sensor offers an excellent response for AA and UA and the linear response range for AA and UA were 1.02 ×10-7-5.23 ×10-4mol.L-1 and 1.43 ×10-7-4.64 ×10-4mol.L-1, the detection limits were 1.12 ×10-8mol.L-1 and 2.24×10-8mol.L-1, respectively. This sensor shows good regeneration, stability and selectivity and has been used for the determination of AA and UA in real human urine and serum samples with satisfied results.

关 键 词：金纳米管阵列 抗坏血酸 尿酸 阳极氧化铝模板 微分差示脉冲伏安 

分 类 号：O646[理学—物理化学]