脑梗死患者颈动脉粥样硬化与血清超敏C反应蛋白水平的相关性分析  

Relative Analysis of Carotid Atherosclerosis in Cerebral Infarction Patients and High-sensitivity C-reactive Protein′s Level

作　　者：苗绘[1] 朱涛[1] 

机构地区：[1]徐州医学院附属第三医院神经内科,江苏省徐州市221003

出　　处：《实用心脑肺血管病杂志》2012年第12期1929-1930,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的探讨脑梗死患者的炎症标记物超敏C反应蛋白(hs-CRP)水平与颈动脉粥样硬化的相关性。方法将107例脑梗死患者按颈总动脉内-中膜厚度(IMT)分为IMT正常组、IMT增厚组和斑块组,或者IMT正常组和动脉粥样硬化组,比较各组间血清hs-CRP水平。结果 IMT增厚组、斑块组血清hs-CRP显著高于IMT正常组,差异均有统计学意义(P<0.05);斑块组血清hs-CRP显著高于IMT增厚组,差异有统计学意义(P<0.05)。动脉粥样硬化组血清hs-CRP显著高于IMT正常组,差异有统计学意义(P<0.05)。结论结合血清hs-CRP水平与颈动脉IMT可以预测脑梗死的发生及预后。Objective To explore the.relationship between high -sensitivity C -reactive protein （hs -CRP） and ca- rotid atherosclerosis in cerebral infarction patients. Methods The 107 cases of cerebral infarction patients with carotid arterial intima - media thickness （IMT） were divided into norpaal ,group, iMT group and IMT thickened plaque group or normal group, IMT group and atherosclerosis, serum hs - CRP levels Were compared between groups. Results Thickening of IMT group, the plaque group was significantly higher than that of IMT serum hs - CRP normal group, the difference was significant （P 〈 0. 05 ） ; the plaque group was significantly higher than that of serum hs - CRP IMT thickened group, the difference was statistically signifi- cant （P 〈0. 05）. Atheroscleresis serum hs -CRP was significantly higher than that in IMT normal group, the difference was statistically significant （P 〈 0. 05）. Conclusion Serum hs - CRP levels combined with carotid IMT can predict the occurrence of cerebral infarction and its prognosis.

关 键 词：脑梗死 动脉粥样硬化 C反应蛋白 

分 类 号：R743.33[医药卫生—神经病学与精神病学]