血液透析和血液透析滤过治疗糖尿病乳酸酸中毒的疗效对比研究  

The Effect Comparison of Hemodialysis and Hemodiafiltration in the Threatment of Lactic Acidosis in Diabetics

作　　者：钟晓琴[1] 周飞[1] 李春国[1] 

机构地区：[1]山东省淄博市临淄区人民医院肾内科,255400

出　　处：《实用心脑肺血管病杂志》2012年第12期1964-1965,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的观察和比较血液透析(Hemodialysis,HD)与血液透析滤过(Hemodiafiltration,HDF)治疗糖尿病乳酸酸中毒临床疗效。方法选择2008年3月—2012年2月在本院相关科室收治的糖尿病乳酸中毒33例为研究对象,将患者分为HD治疗组15例和HDF治疗组18例。比较两组患者的临床疗效和病死率。结果治疗开始后1.5、2.5、24、48h两组患者血乳酸水平和pH值比较,差异均有统计学意义(P<0.05)。HD治疗组患者的病死率高于HDF治疗组,差异有统计学意义(P<0.05)。结论对于糖尿病乳酸酸中毒的患者,常规治疗的基础上应用HDF治疗,具有更好的安全性和抢救成功率,值得在临床上应用和推广。Objective To investigate the different effect of Hemodialysis （HD） andHemadiarlhration （HDF）inthe treatment of lactic acidosis in diabetics. Methods 33 patients were involved in the research, the patents were derided into 2 groups. The patients in the HD group received routine treatment with HD in addition, while patients in the HDF group were trea- ted with HDF in addition. The levels of pH, lactic acid, the rates of deaths were observed. Results Treatment was started af- ter 1.5, 2. 5, 24, 48h in two patients with blood lactate levels and comparison of pH, the differences were statistically signifi- cant （ P 〈 0. 05 ）. The HD in group therapy for patients with mortality rate were higher than those in HDF group, the difference was statistically significant （P 〈 0. 05）. Conclusion For diabetic lactic acidosis in patients, conventional treatment based on the application of HDF treatment, with better sccurity and the success rate of rescue, worthy of clinical application and promo- tion.

关 键 词：肾透析 血液透析滤过 酸中毒 乳酸 糖尿病 

分 类 号：R459.5[医药卫生—治疗学]