广州市城乡养老院≥60岁人群痴呆患者的生存率及相关因素研究  

Survival rate and related Factors in the patients with dementia aged 60 years or over in the urban or rural rest homes in Guangzhou

作　　者：陈健华[1] 唐牟尼[1] 黄若燕[1] 郁俊昌[1] 林康广[1] 佘生林 胡号应[1] 陈映梅[1] 郭伟坚[1] 肖頔[1] 王怀坤[1] 

机构地区：[1]广州医学院附属广州市精神病医院老年精神科,广州510370

出　　处：《中国神经精神疾病杂志》2012年第11期646-650,共5页Chinese Journal of Nervous and Mental Diseases

摘　　要：目的了解广州市城乡养老院无认知障碍老人、轻度认知障碍和痴呆患者的生存率及相关影响因素。方法2001年12月至2002年1月对广州市城乡养老院60周岁及以上年龄老人进行了痴呆患病情况的基线调查,2010年2月对该1105名老人进行生存情况的随访调查。随访内容包括对存活者记录目前患轻度认知障碍或痴呆的情况,对死亡者记录死亡时间和原因。采用Kaplan-Meier曲线描述和比较各组老人的生存率,Cox回归分析各因素对生存率的影响。结果无认知障碍老人、轻度认知障碍及痴呆患者的八年生存率分别为26%、17%、4%(掊2=132.12,P<0.001);年龄等社会人口学特征、痴呆严重程度和日常生活能力等因素中,痴呆严重程度是影响痴呆患者生存率的危险因素,相对危险度(RR)=1.207(P<0.05)。结论预防痴呆的发生能提高老年人的生存率。痴呆程度较重的患者更适合在养老院生活。Objective To investigate the survival rate and related factors in the patients with dementia or mild cognitive impairment and the non-cognitive impairment elders aged 60 years or over in the rest home in urban and rural in Guangzhou. Methods A two stage survey was carried out in 1105 elders aged 60 years or over in the urban and rural rest homes in Guangzhou. The first survey was conducted between Dec 2001 and Jan 2002 and the follow-up study was carried out on Feb 2010. The survey included the status of mild cognitive impairment or dementia and the date and cause of death. Kaplan-Meier curve was used to analyze the survival rate of the elderly. Cox regression was used to analyze the impact of various factors on the surviva ratel. Results After 8 year-follow up, the survival rates of the non-cognitive impairment elders, MCI, and dementia were 26%, 17% and 4%, respectively （Z2= 132.12, P 〈 0.001. Among related factors such as age, dementia severity, activities of daily living and other socio-demographic characteristics, dementia severity was the survival risk factors of dementia patients. Conclusions Prevention of the occurrence of dementia can improve the survival rate in the elderly. Nursing home care is more suitable for patients with severe dementia.

关 键 词：养老院 轻度认知障碍 痴呆 生存率 

分 类 号：R749.1[医药卫生—神经病学与精神病学]