术中放射治疗晚期胰腺癌45例  

Intraoperative radiotherapy for unresectable pancreatic carcinoma

作　　者：黄林平[1] 贾振庚[1] 裴东坡[1] 周正[1] 瑞芹 

机构地区：[1]中日友好医院普外科,北京100029

出　　处：《中华普通外科杂志》2000年第6期355-357,共3页Chinese Journal of General Surgery

摘　　要：目的　探讨术中放射治疗 (简称放疗 )对晚期胰腺癌的疗效。方法　使用直线加速器 ,对 1986～ 1997年期间收住我院 ,伴有严重背痛和腹痛的无法切除的晚期胰腺癌患者 45例进行术中放疗。结果　本组患者背痛和腹痛的完全缓解率为 5 6 % ,部分缓解率为 40 %。平均生存期为7 5个月。同期进行的 30例胰腺癌切除患者 ,其平均生存期为 7个月 ,两者差异无显著意义。结论　术中放疗尽管不能明显延长晚期胰腺癌患者的平均生存期 ,但能明显缓解患者的疼痛 ,提高患者的生活质量 ,仍然不失为一种有效的晚期胰腺癌姑息治疗方法。Objective To study the effect of intraoperative radiotherapy (IORT) on patients with unresectable carcinoma of the pancreas.Method 45 patients with unresectable carcinoma of the pancreas received IORT using a linear accelerator during the period from 1986 to 1997. Preoperatively all patients were tormented by unrelenting abdominal and back pain. Result Abdominal and back pain disappeared in 25 patients (56%), and alleviated in 18 patients (40%) after IORT. The average survival time was 7 5 months for the patients treated with IORT and 7 months for the other 30 patients with resectable carcinomas of the pancreas treated by pancreatectomy during the same period.Conclusion The survival time of patients with unresectable carcinoma of the pancreas undergoing IORT was statistically compareable with that undergoing pancreatic resection, hence, IORT is a good palliative therapy for unresectable carcinoma of the pancreas, which in addition to relieving pain improves the quality of the patient's life.

关 键 词：胰腺肿瘤 放射疗法 手术中 

分 类 号：R735.9[医药卫生—肿瘤]