血脂紊乱在儿童青少年代谢综合征中的意义  

The role of dyslipidemia in metabolic syndrome in children and adolescents

作　　者：朱伟芬(综述)[1] 梁黎(审校)[1] 

机构地区：[1]浙江大学医学院附属儿童医院内分泌科,杭州310003

出　　处：《国际儿科学杂志》2012年第6期569-572,共4页International Journal of Pediatrics

基　　金：十一五国家科技支撑计划项目（2009BAI80801）;浙江省科技厅重大与高发疾病防治技术专项（2008C03002-1）

摘　　要：代谢综合征是一种涉及多种代谢异常、与心血管疾病紧密联系的疾病状态。我国和美国儿科学会新定义的儿童青少年代谢综合征血脂紊乱主要为高甘油三酯、高非高密度脂蛋白胆固醇和低高密度脂蛋白胆固醇血症。研究证实，儿童期血脂紊乱在成年期疾病如动脉粥样硬化、高血压的发生发展中起重要作用，与代谢综合征、胰岛素抵抗和高血糖的发生亦密切相关。该文就血脂紊乱在儿童青少年代谢综合征中的地位及作用的进展作一综述。] The metabolic syndrome is composed of various metabolic disorders, which is associated with cardiovascular disease. Dyslipidaemia in the metabolic syndrome in children and adolescents, as defined by A- mexican Academy of Pediatrics and Chinese Society of Pediatrics, is characterised by elevated triglycerides and non-high-density lipoprotein cholesterol ag well as low high-density lipoprotein cholesterol concentrations. Good evidence confirms that dyslipidaemia in. children plays a vital role in the development of adulthood disease, such as atherosclerosis and hypertension, also closely related to metabolic syndrome,insulin resistance and hyperglycemia. Here we reviewed the the role of dyslipidemia in metabolic syndrome in children and adolescents.

关 键 词：代谢综合征 血脂紊乱 心血管疾病 儿童 青少年 

分 类 号：R589[医药卫生—内分泌]