过夜配戴角膜矫形镜(OK镜)后角膜曲率及厚度变化  

Changes in corneal radius and thickness in response to overnight wear of orthokeratology lenses

作　　者：杨晓[1] 龚向明[1] 魏玲[1] 戴祖优[1] 李树兴[1] 

机构地区：[1]中山医科大学中山眼科中心,510060

出　　处：《中国实用眼科杂志》2000年第5期272-276,共5页Chinese Journal of Practical Ophthalmology

摘　　要：了解过夜配戴角膜矫形镜 (OK镜 )后早期角膜曲率、角膜厚度及屈光度的变化。方法 :14个中低度近视患者 (平均屈光度 -3 .89± 1.2 6D) 2 5眼 ,随机分成 2组分别配戴 Dk值不同的角膜矫形镜 :BE角膜矫形镜组 (7人 12眼 ,Dk≈ 14 0 ) ;E& E角膜矫形镜组 (7人 13眼 ,Dk=58)。采用夜戴方式 ,平均配戴时间 10 .76± 1.2 7小时。用 Orbscan角膜地形图系统检查配戴 1晚后角膜曲率、角膜厚度的改变。同时记录裸眼视力及屈光度的改变。结果 :配戴 1晚后所有患者的中央及周边的角膜均增厚 (P<0 .0 5)。Orbscan角膜地形图 Sim K值在垂直轴及水平轴均变平 (垂直轴 ΔSim K:0 .94± 0 .56D,P<0 .0 0 1;水平轴 ΔSim K:0 .996± 0 .68D,P<0 .0 0 1)。裸眼视力平均提高 0 .4± 0 .2 4 (P<0 .0 0 1)。屈光度平均减少 -1.85± 0 .82 D (P<0 .0 0 1)。Dk值不同的 2组之间中央及颞上方位点角膜增厚程度的差别有统计学意义。结论 :过夜配戴角膜矫形镜后减低近视屈光度的效果明显。初次过夜配戴角膜矫形镜可导致角膜厚度轻度增加。Objective:To assess early changes in response to overnight wear of orthokeratology lenses.Methods:Two kinds of orthokeratology lenses with different Dk values were fitted to 25 eyes of 14 patients(average refraction:-3 89±1 26D).The patients were randomly divided into two groups by the lenses Dk values:one group with BE orthokeratology lenses(7 patients 12 eyes,Dk≈140);The other group with E&E orthokeratology lenses(7 patients 13 eyes,Dk=58).All eyes were free of pathology.All patients wear lenses overnight.The average wear time was 10 76±1 27 hours.Changes in the radius and thickness of the cornea were measured with Orbscan corneal topography system after 1 night of lens wear.And unaided acuity and refractive changes were recorded.Results:Significant increases were observed both in centeral and peripheral cornea thickness(P<0 01).Simulated keratometry(SimK)reading indicated significant flattening in both the horizontal(ΔSimK:0 94±0 56D,P<0 001)and vertical meridians(ΔSimK:0 996±0 68D,P<0 001).The unaided acuity significant increases by 0 4±0 24.Refraction significant decreases -1 85±0 82D.The difference of cornea thickness increases in centeral and superotemporal corneal locations between 2 groups has statistical significance.Conclusion:This study showed that orthokeratology is effective on reducing the refraction of myopia after overnight wear.And the cornea thickness increases slightly after 1 night wear.

关 键 词：角膜矫形学 角膜地形图 角膜曲率 角膜厚度 OK镜 

分 类 号：R778.3[医药卫生—眼科]