胸外孤立性纤维瘤MRI特征及病理表现  

MRI Features and Pathologic Appearances of Solitary Extra-pleural Fibrous Tumors

作　　者：邱传亚[1] 张勇[1] 赵丽华[2] 

机构地区：[1]民航总医院放射科,北京100123 [2]民航总医院病理科,北京100123

出　　处：《中国医学影像学杂志》2012年第12期894-896,900,共4页Chinese Journal of Medical Imaging

摘　　要：目的探讨胸外孤立性纤维瘤的MRI特征表现及其与病理改变的关系。资料与方法回顾性分析6例经手术后病理证实的孤立性纤维瘤患者的MRI表现,并与病理改变进行对照。结果 6例患者中,肿块位于头颈部4例,盆腔2例。MRI显示5例肿瘤呈圆形或椭圆形,1例呈不规则形。所有肿块边缘光滑、界限清晰,T1信号均匀,与肌肉相似,T2呈均匀稍高信号或条纹状高低相间稍高信号,强化显著、均匀。病理显示肿瘤由散在分布密集区或稀疏区的梭形细胞组成,其间含有粗细不均的胶原纤维。免疫组化染色见肿瘤CD34/Vim均呈阳性,Bcl-2阳性3例,S-100弱阳性3例,肌动蛋白弱阳性1例。结论胸外孤立性纤维瘤的MRI表现具有T2脂肪抑制均匀高信号或条纹状高信号、显著强化的特征,MRI对其诊断具有一定价值,确诊需依靠病理结果。Purpose To investigate the relationship between MRI features and pathologic appearances of extra-pleural fibrous solitary tumors （ESFTs）. Materials and Methods MRI and pathologic findings in 6 cases with pathology proven ESFT were analyzed retrospectively. Results The tumor was found in the head and neck in 4 cases and in the pelvis in 2 cases. MRI showed round or oval well- circumscribed solitary masses in 5 cases and irregularly shaped mass in 1 case. All lesions appeared slightly low signal on T1WI; homogeneous or heterogeneous high signal on T2WI, with obviously marked enhancement. Pathology examination showed ESFTs were composed of fusiform, among which there were collagen fibers. Immunohistochemical staining showed CD34/Vim-positive cells in all cases, Bcl- 2-positive cells in 3 cases, weak S-100- positive cells in 3 cases and weak SAM- positive cells in 1 case. Conclusion MRI features of ESFT with high signals on T2WI and marked enhancement are specific. However, the final diagnosis depends on the pathology examination and immunohistochemical staining.

关 键 词：纤维瘤 头颈部肿瘤 盆腔肿瘤 磁共振成像 病理学 外科 

分 类 号：R734.4[医药卫生—肿瘤]