石斛多糖的抗菌作用研究  

Study on the Value of Polysaccharide in Dendrobium Candidum in Antibacterial Action

作　　者：张周英[1] 杨成密[1] 蓝忠[1] 黄群[1] 梁林源[1] 

机构地区：[1]茂名市人民医院药剂科,广东茂名525000

出　　处：《中国医药指南》2012年第33期439-440,共2页Guide of China Medicine

摘　　要：目的研究石斛多糖的抗菌作用,为进一步推广石斛的临床应用提供实验数据支持。方法采用滤纸片抑菌圈法比较铁皮石斛多糖与金钗石斛多糖对金黄色葡萄球菌、大肠杆菌、肺炎球菌的抗菌作用。结果铁皮石斛多糖对金黄色葡萄球菌、大肠杆菌、肺炎球菌抑菌圈的直径分别为(2.72±1.29)mm、(12.42±2.12)mm、(4.53±2.12)mm,金钗石斛多糖对金黄色葡萄球菌、大肠杆菌、肺炎球菌抑菌圈的直径分别为(11.40±1.73)mm、(10.25±1.90)mm、(7.18±2.39)mm,组间比较差异具有统计学意义(t=15.578、3.526、6.849,P<0.05)。结论两种石斛多糖均对金黄色葡萄球菌、大肠杆菌、肺炎球菌抑菌均具有明显的抑菌作用,金钗石斛多糖抑菌作用更为明显。Objective To sutdy the vaule of polysaccharide in dendrobium candidum antibacterial function,to further promote the clinical application of dendrobium to provide the data support.Methods the filter paper is polysaccharide in dendrobium candidum iron and JinChai polysaccharide in dendrobium candidum to staphylococcus aureus,escherichia coli,pneumococcus antibacterial function.Methods The filter paper is polysaccharide in dendrobium candidum iron and JinChai polysaccharide in dendrobium candidum to staphylococcus aureus,escherichia coli,pneumococcus antibacterial function.Results Iron polysaccharide in dendrobium candidum to staphylococcus aureus,escherichia coli,pneumococcus antibacterial circle diameter of respectively（2.72±1.29）mm,（12.42±2.12）mm,（4.53±2.12）mm,JinChai polysaccharide in dendrobium candidum to staphylococcus aureus,escherichia coli,pneumococcus antibacterial circle diameter of respectively（11.40±1.73）mm,（10.25±1.90） mm,（7.18±2.39）mm,comparative differences between groups are statistically significant（t=15.578,3.526,6.849,P 0.05）.Conclusions Two kinds of polysaccharide in dendrobium candidum are staphylococcus aureus,escherichia to app： ds： escherichia coli,pneumococcus antibacterial all has obvious bacteriostatic action,JinChai polysaccharide in dendrobium candidum antibacterial effect is more apparent.

关 键 词：石斛多糖 铁皮石斛 金钗石斛 抗菌作用 

分 类 号：R730.51[医药卫生—肿瘤]