胃癌患者生命质量测定量表EORTC QLQ-STO22中文版的制定和评价  

Development and Evaluation on Chinese Version of Measurement Instrument of Quality of Life for Patients with Stomach Cancer:EORTC QLQ-STO22

作　　者：孟琼[1] 罗家洪[1] 万崇华[2] 许传志[1] 李高峰[3] 寸英丽[4] 

机构地区：[1]昆明医科大学公共卫生学院流行病与卫生统计学系,云南昆明650031 [2]广东医学院人文与管理学院暨生命质量与应用心理研究中心,广东东莞523808 [3]云南省肿瘤医院胸外科,云南昆明650118 [4]云南省肿瘤医院腹部外科,云南昆明650118

出　　处：《昆明医科大学学报》2012年第10期34-38,共5页Journal of Kunming Medical University

基　　金：国家自然科学基金资助项目(81273185);云南省社会发展科技计划项目(2008CD055)

摘　　要：目的研制欧洲癌症研究与治疗组织开发的生命质量测定量表EORTC QLQ-STO22的中文版,评价其心理测量特性.方法通过量表的翻译、回译及文化调适制定中文版的EORTC QLQ-STO22,并对86例住院的胃癌患者进行的生命质量测定后对量表进行了评价.采用的统计学方法有相关分析,探索性因子分析,配对t检验.结果量表所有领域的重测相关系数均大于0.70;所有领域的克朗巴赫系数α均在0.70以上;各条目与其所在领域间有高度相关而与其他领域间仅有低度相关;提取9个公因子,累计方差贡献率为82.28%,进行了方差最大旋转后结果 9个公因子基本反映了9个领域;在治疗4周后EORTC QLQ-STO22中文版能发现除了躯体形象领域外,其余各领域得分的改变.结论 EORTC QLQ-STO22中文版具有好的信度、效度和适中的反应度,可与EORTCQLQ-C30一起应用于临床,作为我国胃癌患者生命质量的测评工具.Objective To introduce how to develop the Simplified Chinese version of EORTC QLQ-STO22 and evaluate the psychometric characteristics of this instrument.Methods The Simplified Chinese version of the EORTC QLQ-STO22 was developed by translation and back-translation and cultural adaptation,and was evaluated after we measured the quality of life of 86 in-patients with stomach cancer by using this instrument.The statistic method included correlation analysis,exploratory factor analysis,and paired t-test.Result The test-retest correlation coefficients（r）for all domains were greater than 0.70.Cronbach＇s coefficients for all domains were greater than 0.70.There were strong correlations between items and their own domains,but weak correlations between items and other domains.9 principal components were abstracted from 22 items,and the contribution rate of accumulative total of variance was 84.7%.These 9 principal components basically reflected the 9 domains of the instrument after varimax orthogonal rotation.The instrument could find the change of the scores of the other domains except of body image domain after 4 weeks treatment.Conclusion The simplified Chinese version of EORTC QLQ-STO22 is of good validity,reliability and responsiveness and can be used as a measurement instrument for survey and evaluation of QOL in stomach cancer patients in China with the Chinese version of EORTC QLQ-C30.

关 键 词：胃肿瘤 生命质量 量表 中文版 

分 类 号：R73-31[医药卫生—肿瘤] R730.7[医药卫生—临床医学]