美常安联合盐酸小檗碱灌肠治疗急性腹泻临床观察  

Effect observation of Medlic-S combined with berberine hydrochloride enema in acute diarrhea

作　　者：耿滢 刘晓丽[2] 

机构地区：[1]铁岭卫生职业学院临床教研室,辽宁铁岭112000 [2]辽宁省铁岭市中心医院感染病房,辽宁铁岭112000

出　　处：《中国医药科学》2012年第23期76-77,79,共3页China Medicine And Pharmacy

摘　　要：目的观察美常安联合盐酸小檗碱灌肠治疗急性腹泻的疗效及安全性。方法随机将急性腹泻的住院患者98例分为观察组和对照组各49例,观察组给予美常安口服联合盐酸小檗碱灌肠及常规治疗,对照组予蒙脱石散口服及常规治疗。治疗72h后比较两组临床疗效。结果治疗后72h两组腹泻次数均下降,观察组从(7.8±3.2)次下降到(3.1±2.4)次,对照组从(7.9±3.0)次下降到(4.2±2.0)次,观察组优于对照组,差异有统计学意义(P<0.05)。结论美常安口服联合盐酸小檗碱灌肠可明显改善急性腹泻病情,疗效尚优于单用思密达,改善肠道菌群失调,安全性良好。Objective To observe the clinical effect of Medlic-S combined with berberine hydrochloride enema in acute diarrhea.Methods 98 cases with acute diarrhea were randomly divided into observation group（49 cases） and control group（49 cases）.Observation group was given Medlic-S and berberine enema.Control group was received montmorillonite powder oral.3 days was set for a course of treatment.The clinical efficacy and diarrhea 2 groups after treatment were observed.Results The total effective rate of observation group was higher than of control group,and the difference was statistically significant（P 0.05）.The diarrhea days of both of two groups were as follows.The observation group decreased to 3.1±2.4 from 7.8±3.2,that control group decreased to 4.2±2.0 from 7.9±3.0.The difference was significant（P 0.05）.Conclusion Medlic-S combined with berberine enema in acute diarrhea has a significant clinical effect with high security and is worthy of clinical application.

关 键 词：急性腹泻 美常安 盐酸小檗碱 肠道菌群失调 

分 类 号：R574[医药卫生—消化系统]