蝎龙接骨散质量标准研究  

Quality Standard of Xielongjiegu Powder

作　　者：王亚洲[1] 

机构地区：[1]广西医科大学第四附属医院,柳州545005

出　　处：《黑龙江医药》2012年第6期845-847,共3页Heilongjiang Medicine journal

摘　　要：目的:建立蝎龙接骨散新的质量标准。方法:采用薄层色谱法(TLC)定性鉴别处方中的血竭、红花和当归;采用高效液相色谱法对羟基红花黄色素A和阿魏酸进行含量测定。用InertsilC8-3柱,乙腈-0.2%磷酸-四氢呋喃(23:75:2)为流动相,流速为1.0mL/min,检测波长为340nm。结果:TLC特征斑点明显、专属性强。羟基红花黄色素A和阿魏酸的线性范围分别为11.13～111.35μg/mL和3.42～34.2μg/mL;平均加样回收率分别为100.35%和99.43%(n=6)。结论:所建的新标准可用于蝎龙接骨散的质量控制。Objective ：To study a new quality standard of xiclongjiegu powder. Methods：Sanguis draconis, flos carthami and radix angelicae sinensis in the the formula were identified qualititively by TLC The contents of hydroxysafflor yellow A and ferulic acid were determined by HPLC with a Inertsil C8 -3 column. The mobile phase was acetonitrile -0. 2% phosphoric acid - tetrahydrofuran （ 23 ： 75 ： 2） with a flow rate at 1.0 mL/min. Detection wavelength was 340nm. Results： The TLC spots were clear and specific. ＇File linear ranges for hydroxysaffior yellow A and ferulic acid ,sere 11.13 - 111. 35μg/mL and 3.42 - 34. 2μg/mL respectively. The average recoveries were 1130. 35 % and 99. 43% （ n = 6）. Conclusion：Tile new estab- lished standard can be used for the quality control of xielongjiegu powder.

关 键 词：蝎龙接骨散 羟基红花黄色素A 阿魏酸 高效液相色谱法 薄层色谱法 质量标准 

分 类 号：R28[医药卫生—中药学]