甲状腺癌^(131)I显像假阳性的分析及鉴别诊断  

The analysis and diferentiate diagnosis of false positive ^(131)I imaging in metastatic thyroid carcinoma

作　　者：陈可靖[1] 

机构地区：[1]上海医科大学附属中山医院核医学科,上海200032

出　　处：《国外医学（放射医学核医学分册）》2000年第1期11-14,共4页Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)

摘　　要：:1 3 1 　 I显像是诊断分化型甲状腺转移癌的特异方法 ,有关报道显示该方法诊断甲状腺转移癌的特异性为 96 % ,灵敏度为 80 %。但近年来也有不少报道指出假阳性结果的存在 ,如额窦粘液囊肿、胸腺、肺癌、乳房、食道良性狭窄、结肠移植物、胃上移、肾囊肿等均可见有 1 3 1　 I的蓄积 ,尽管其发生率不高 ,但常干扰诊断 ,导致病员接受不必要的照射。因此 ,对假阳性结果的出现部位 ,产生原因及可能的鉴别方法应该有所了解。为了得到正确诊断 ,可合并应用其他影像诊断方法 ,或辅以 2 0 1　 Tl显像 ,或辅以测定血中人甲状腺球蛋白 ( h- TG) 。I imaging is a specific method for demonstrating metastatic differentiated thyroid carcinoma. It was reported that its specificity and sensitivity were 96% and 80% respectively, but false positive results also existed: many tissues besides thyroid can accumulate 131 I such as frontal sinus mucocele, thymus, lung carcinoma, breast, esophagus benign stricture, colon graft, gastric pull up, renal cyst etc. Although its incidence is low,it often misleads the diagnosis and brings unnecessary radiation to the patients. So it is necessary to make sure the location, cause and possible differentiate way of false positive results. In order to get correct diagnosis results, it is suggested to use other imaging modality or 201 Tl imaging together and detect serum h Tg at the same time.

关 键 词：分化型甲状腺癌 ^131I显像 假阳性 鉴别诊断 

分 类 号：R736.1[医药卫生—肿瘤]