二色桌片参的化学成分研究──Ⅱ　二色桌片参多糖-1,一种新的岩藻聚糖  

STUDIES ON THE CHEMICAL CONSTITUENT FROM SEA CUCUMBER MENSAMARIA INTERCEDENS──Ⅱ.PMI-1, A NOVEL FUCOSAN

作　　者：吴萍茹 方金瑞 黄维真 郑忠辉[2] 黄耀坚[2] 苏文金[2] 

机构地区：[1]福建海洋研究所,厦门361012 [2]厦门大学肿瘤细胞工程国家专业实验室,厦门361005

出　　处：《中国海洋药物》2000年第2期4-7,10,共5页Chinese Journal of Marine Drugs

基　　金：福建省重中之重项目

摘　　要：利用乙醇沉淀分级技术从二色桌片参双酶水解液里分离到一种纯的活性多糖，定名PMI-1。用高效薄层层析法鉴定其组成的单糖，发现PMI-1只含有L-岩藻糖。根据其分析结果和理化特性，PMI－1应是由若藻糖基和岩藻糖-4硫酸酯基组成的均多糖。研究PMI－1的核磁共振谱，可认定它是一种具有直链的和α1－α联接的均多糖。因此它是一种新的岩藻聚糖。Using double enzymes digestion and fractionations by precipitation with alcohol, a pure active polysaccharide PMI-1 was obtained from the dried body wall of Mensamaria intercedens. Monosaccharide composition was identified by thin-layer chromatography, the results indicate that PMI-1 only consisits of L-fucose. According to analytical and chemicophysical data, PMI-1 seemed to be homosaccharide consisted of fucose and fllcose-4sulfate with the molar ratio of 1: 1. Studied on the 1 HNMR and 13MNMR data of PMI-1 showed that PMI-1 had a straightsaccharide chain and α1-α linkage.

关 键 词：于色桌片参多糖 均多糖 岩藻聚糖 化学成分 

分 类 号：R914.1[医药卫生—药物化学]