米氮平联合替加色罗治疗功能性消化不良临床研究  

Clinical Study of the Effect of Combination Application of Mirtazapine and Tegaserod on Functional Dyspepsia

作　　者：张林[1] 江艳燕[1] 李莲[1] 邓晓玲[1] 顾雪梅[1] 

机构地区：[1]湖北医药学院附属人民医院,湖北十堰442000

出　　处：《现代生物医学进展》2012年第33期6558-6560,6511,共4页Progress in Modern Biomedicine

摘　　要：目的:探讨米氮平联合替加色罗治疗功能性消化不良临床疗效。方法:选择符合2006年罗马Ⅲ标准的62例功能性消化不良患者(均伴随不同程度抑郁焦虑症状),随机分为治疗组(米氮平联合替加色罗)与对照组(替加色罗),观察治疗前后症状变化,并按症状进行分级评分评估。结果:经用米氮平联合替加色罗治疗后病人功能性消化不良及全身症状均能显著缓解,且治疗中未发现明显不良反应。结论:米氮平联合替加色罗是一种治疗功能性消化不良较理想的治疗方案。Objective： To investigate the clinical efficacy of combination application of mirtazapine and tegaserod on functional dyspepsia （FD）. Method： 62 cases of patients with functional dyspepsia according to Rome Ⅲ criteria （all accompanied with varying degrees of depression and anxiety symptoms） were randomly divided into treatment group （mirtazapine joint for tegaserod） and control group （tegaserod）. Symptoms classification and depression rating scale score were analyzed. Results： Functional dyspepsia and systemic symptoms alleviated significantly administered with mirtazapine and tegaserod, and no side effect was found. Conclusion： Combination of Mirtazapine and tegaserod is an ideal treatment project for FD.

关 键 词：米氮平 替加色罗 功能性消化不良 

分 类 号：R573[医药卫生—消化系统]