肝脏癌肉瘤的临床病理特征研究  

Clinicopathologic features of the liver carcinosarcoma

作　　者：邱莎莎[1] 邓晓[1] 李代强[2] 张文平[1] 

机构地区：[1]赣南医学院基础医学院,江西赣州341000 [2]中南大学湘雅医学院附属第二医院病理科,湖南长沙410011

出　　处：《重庆医学》2012年第36期3859-3861,F0003,共4页Chongqing medicine

摘　　要：目的探讨肝脏癌肉瘤的临床病理特征及其鉴别诊断。方法回顾性分析4例肝脏癌肉瘤的病理特征并结合文献进行复习。结果肿瘤中有明确的上皮癌成分和肉瘤成分,两者之间分界清楚,无移行过渡,免疫组化显示肿瘤分别表达上皮源性和间叶源性的标志物。结论肝脏癌肉瘤是一种罕见的肝恶性肿瘤,具有独特的临床病理特征,可能来自多潜能干细胞,为预后差的肿瘤。Objective To investigate the clinicopathological characteristics and differential diagnosis of carcinosarcoma of the liver.Methods Clinicopathological characteristics of 4 cases were retrospectively analyzed,along with a review of related literatures.Results The tumor had distinct components of the malignant epithelial component and the sarcomatous component,and no transitional areas were detected between carcinoma and sarcoma.Mmunohistochemically,the tumor expressed the malignant epithelial component marker and the sarcomatous component marker respectively.Conclusion Carcinosarcoma of the liver is a rare malignancy of the liver,which had unique clinicopathological characteristics.It may be arised from multipotential stem cells and reveals poor prognosis.

关 键 词：肝 癌肉瘤 诊断 临床病理特征 

分 类 号：R735.7[医药卫生—肿瘤]