多层螺旋CT灌注成像在肾脏肿瘤诊断中的应用价值  

Application of multi-slice CT perfusion imaging in diagnosis of renal tumors

作　　者：王雪莉[1] 胡柯军[1] 激扬[1] 

机构地区：[1]西安医学院第一附属医院影像科,西安710077

出　　处：《山西医科大学学报》2012年第12期941-944,976,共5页Journal of Shanxi Medical University

摘　　要：目的探讨多层螺旋CT灌注成像对肾脏良恶性肿瘤的诊断价值。方法本研究共包括42例肾细胞癌及15例肾脏良性肿瘤,均有完整的临床和病理资料。对所有病例先行常规肾脏CT平扫,然后对选定层面进行CT灌注扫描。通过后处理软件分别测量其灌注参数血流量(blood flow,BF)、血容量(blood volume,BV)、平均通过时间(mean transit time,MTT)和表面通透性(permeability surface,PS)值,并进行分析。结果肾细胞癌组灌注参数BF、BV、PS平均值均明显高于肾脏良性肿瘤及对侧正常肾脏髓质,差异具有统计学意义(P<0.001),而MTT平均值的差异无统计学意义(P>0.05)。肾脏良性肿瘤组灌注参数BF、BV、PS平均值均明显低于对侧正常肾脏髓质,差异具有统计学意义(P<0.001),而MTT平均值的差异无统计学意义(P>0.05)。结论 CT灌注成像可以较好地反映肾脏肿瘤的血流动力学情况,有助于术前判断肿瘤的良恶性。Objective To investigate the diagnostic value of CT perfusion parameters for tumors of kidney.Methods Forty-two cases of renal cell carcinoma and 15 cases of renal tumors,which had integrated clinical information and pathological data,were enrolled.CT perfusion scanning ran at the maximum slice of tumor after plain scanning in all cases.The post-processing software was used to detect the blood flow（BF）,blood volume（BV）,mean transit time（MTT） and permeability surface（PS）.Results The mean values of BF,BV,PS in renal cell carcinoma were significantly higher than those in benign tumors of kidney and contralateral kidney（P0.001）,however,no statistical difference was found in MTT（P0.05）.The mean values of BF,BV,PS in benign tumor of kidney were significantly lower than those of normal contralateral kidney（P0.001）,but there was no statistical difference in MTT（P0.05）.Conclusion CT perfusion can reflect the morphological characteristics of tumors of kidney.CT Perfusion may be used to evaluate the benign or malignat tumors of kidney.

关 键 词：多排螺旋CT 灌注成像 肾脏肿瘤 

分 类 号：R737.11[医药卫生—肿瘤]