VG染色在慢性肝病组织中的应用  

作　　者：姜晶[1] 王彩芹[1] 

机构地区：[1]北华大学附属医院病理科,132011

出　　处：《当代医学》2013年第1期19-20,共2页Contemporary Medicine

摘　　要：目的应用VG染色对肝活检和尸检标本进行观察。探讨胶原纤维在慢性肝病组织内的分布及肝纤维化的形成机制。方法应用VG染色对40例肝活检和尸检标本进行检测,HE染色确定病理诊断。光镜下观察,VG染色显示慢性肝病组织中的胶原纤维。结果 9例慢性肝炎中,轻型慢性肝炎2例,慢性中度肝炎4例,重度慢性肝炎3例;31例肝硬化中不完全分割性型3例,细结节型17例,粗结节型11例。经VG染色后胶原纤维染成粉红色,并形成间隔分割肝组织。结论胶原纤维可能起源于贮脂细胞和成纤维细胞,VG染色对慢性肝病有诊断意义。Objective To explore the distribution of collagen fiber in chronic liver disease tissue and hepatic fibrosis formation mechanism, VG staining was used to detect liver biopsy and autopsy specimens. Methods VG staining was used to detect 40 cases of liver biopsy and autopsy specimens, and HE staining was used to determine pathological diagnosis. VG staining showed the collagen fibrils of chronic liver diseases tissue under light microscope. Results Chronic hepatitis cases were 9, and low grade chronic hepatitis 2, moderate chronic hepatitis 4, serious chronic hepatitis 3; liver cirrhosis cases were 31,and incomplete partition type liver cirrhosis3, fine nodular cirrhosis 17, coarse nodular cirrhosis 1 I. By VG staining collagen fibers were dyed pink, and the form hepatic tissue interval. Conclusion Collagen fiber may originate in fat storing cells and fibroblasts. VG stains may have diagnostic significance in chronic liver disease.

关 键 词：慢性肝炎 肝硬化 胶原纤维 

分 类 号：R575[医药卫生—消化系统]