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作 者:刘冉[1] 李加青[1] 李涛[1] 曾婧[1] 潘间英[1] 丁小燕[1] 唐仕波[1]
机构地区:[1]眼科学国家重点实验室//中山大学中山眼科中心,广东广州510060
出 处:《中山大学学报(医学科学版)》2012年第6期841-847,共7页Journal of Sun Yat-Sen University:Medical Sciences
基 金:国家自然科学基金青年基金(81100685);眼科学国家重点实验室青年引导基金(2010年);广东省自然科学基金(10151008901000055)
摘 要:【目的】研究息肉样脉络膜血管病变(PCV)的频域光相干断层扫描图像(SD-OCT)特征并分析其临床意义。【方法】对经眼底检查、眼底彩照、荧光素血管造影和吲哚青绿造影确诊的连续PCV患者的SD-OCT图像进行分析,分析PCV在SD-OCT上的主要表现形式。【结果】共95例患者(106眼)纳入该研究,其中18眼(16.98%)出现广泛性出血性色素上皮层脱离(mhPED)伴或不伴视网膜下大出血(MSH),总范围大于12个视盘面积;在无mhPED/MSH的98眼中,78眼(79.59%)可见双线征,71眼(72.45%)见局限性视网膜色素上皮脱离,42眼(42.86%)见拇指样隆起息肉病变,65眼(66.33%)见视网膜下积液,20眼(20.41%)见视网膜层间积液,29(29.59%)眼见局限性视网膜下出血。【结论】双线征、色素上皮脱离、视网膜下积液、拇指样息肉病灶以及视网膜下出血是PCV在SD-OCT上常见的5种表现形式,其中以双眼线征和色素上皮脱离最为常见。[Objective] To investigate the spectral-domain optical coherence tomography (SD-OCT) findings in eyes with polypoidal choroidal vasculopathy (PCV). [Methods] This observation recruited 106 eyes of 95 PCV patients confirmed by fundus photography, fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA). Main manifestations and signs on OCT were analyzed. [ Results] Massive hemorrhagic pigment epithelial detachment (mhPED) with/without massive subretinal hemorrhage (MSH) was shown in 18 of 106 eyes (16.98%) with PCV on SD-OCT. In the 98 eyes without mhPED/MSH, double-layer sign (DLS) was detected in 78 eyes (79.59%), local pigment epithelial detachment (PED) was present in 71 eyes (72.45%), 42 eyes (42.86%) had thumb-like polyps (TLP), subretinal fluid (SRF) and intra-retinal fluid (IRF) were seen in 65 eyes (66.33%) and 20 eyes (20.41%) respectively, local subretinal hemorrhage (SRH) was detected in 29 eyes (29.59%). [Conclusion]DLS, PED, TLP, SRF, and SRH, are the main OCT signs of PCV on SD-OCT, while DLS and PED are the most common ones.
关 键 词:息肉样脉络膜血管病变 频域光相干断层扫描 双线征 视网膜色素上皮脱离
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