聚胍类抗菌材料对牙周塞治剂微拉伸粘结强度的影响  

Microtensile Bond Strength of Periodontal Dressing Modified with Oligo-Guanidine Antimicrobial Agents

作　　者：陈晓霞[1,2] 刘白玲[3] 何帅 王彦亮[4] 朱莉[1] 麻健丰[4] 

机构地区：[1]温州医学院口腔医学院,浙江温州325000 [2]解放军第118医院口腔科 [3]中科院成都有机化学研究所 [4]温州医学院附属口腔医院

出　　处：《口腔医学研究》2012年第12期1250-1253,共4页Journal of Oral Science Research

基　　金：全军医疗科研"十一五"计划基金项目(06MA151);南京军区医疗卫生专业人才"122工程"学科带头人培养计划;南京军区医疗科研"十一五"计划基金项目(Y07010)

摘　　要：目的:通过测定6种聚胍类抗菌材料不同含量的牙周塞治剂与牙釉质的微拉伸粘结强度,探讨不同抗菌材料添加量对牙周塞治剂粘结性能的影响。方法:150颗新鲜拔除的无龋第三磨牙颊侧制备出约5mm×5mm的牙釉质平面,分别将添加不同浓度聚单胍(PHGC)、有机硅改性聚单胍(PHGC-Si-1、PHGC-Si-1.5)、聚双胍(PBG)、有机硅改性聚双胍(PBG-Si-3、PBG-Si-4)的牙周塞治剂调拌好后堆在第三磨牙颊侧釉质平面上,将制备好的样本切成截面为2mm×2mm的条状试件用于微拉伸强度测试。结果:在牙周塞治剂中添加PHGC、PH-GC-Si-1,含量小于0.50%,PBG含量小于0.25%,PBG-Si-3含量小于0.45%时,对塞治剂粘结力的影响很小。添加各种浓度的PHGC-Si-1.5、PBG-Si-4均对塞治剂的粘结力影响较大。结论:在牙周塞治剂中添加上述各种抗菌材料对塞治剂的粘结力均有不同程度的影响,而且随着抗菌材料中硅的含量的增加影响逐渐增大。Objective：To study the effects of varied contents of different oligo-guanidine antimicrobial agents on the microtensile bond strength of periodontal dressing.Methods：One hundred and fifty non-carious human third molars were used in this study.The buccal enamel surfaces of the teeth were flat to obtain a 5mm×5mm enamel flat surface.Periodontal dressings with six kinds of antimicrobial agents（PHGC,PHGC-Si-1,PHGC-Si-1.5,PBG,PBG-Si-3,PBG-Si-4） were placed on the enamel surfaces.The specimens were then sectioned to sticks with a cross-section area of 2mm×2mm for microtensile bond strength tests.Result：Microtensile bond strength of periodontal dressing receives little effect,when the concentration of PHGC and PHGC-Si-1 is less than 0.50%,the concentration of PBG is less than 0.25%,and the concentration of PBG-Si-3 is less than 0.45%,respectively.Microtensile bond strength of periodontal dressing will decrease,no matter what the concentration of PHGC-Si-1.5 and PBG-Si-4 changes.Conclusion：Microtensile bond strength of periodontal dressing with six kinds of antimicrobial agents has different degrees of changes,and the effect is increased along with the increased silicon content found in antibacterial material.

关 键 词：牙釉质 牙周塞治剂 抗菌材料 微拉伸粘结强度 

分 类 号：R783.1[医药卫生—口腔医学]