大豆异黄酮及其衍生物对宫颈癌细胞增殖的影响  

Effect of Soyisoflavone and Its Derivatives on Proliferation of Human Cervical Carcinoma Cell Line:A Review

作　　者：蒋葭蒹[1] 冉昇[1] 吴婷婷[1] 顔云荞 朱双良[1] 任娇[1] 

机构地区：[1]扬州大学旅游烹饪学院,江苏扬州225127

出　　处：《大豆科学》2012年第6期1017-1020,1023,共5页Soybean Science

基　　金：江苏省普通高校研究生科研创新计划(CXLX12_0941)

摘　　要：近年来的研究发现大豆异黄酮及其衍生物具有抗癌、抗氧化、抗突变等多种药理学作用。目前宫颈癌仍是严重威胁广大女性生命的恶性肿瘤之一,因此开发新的药物非常重要。本文对大豆异黄酮及其衍生物对宫颈癌细胞(Hela、CaSki、Me180、Siha)增殖方面的影响进行了综述,并对其作用途径进行了归纳总结,为研究开发宫颈癌药物提供了新思路。Recently soybean and its derivatives have been found to be a potential resource,full of pharmacological properties,such as antioxidant,anticancer and antimutation etc,numerous studies have reported about the pharmacological functions of soyisoflavone,which is one of the most important components in soybean and its phytochemicals.As the most serious disease threatening to women＇s lives worldwide,cervical cancer is still a tough issue which amends some brand new innovation of drugs to patients＇ therapy.In this paper,the effect about cell proliferation of soyisoflavone and its derivatives on human cervical carcinoma cell line（Hela,CaSki,Me180,Siha）is summarized.The concrete mechanism will be sum up and provide a new clue for cervical cancer therapy.

关 键 词：大豆异黄酮 衍生物 宫颈癌细胞 增殖 

分 类 号：S565.1[农业科学—作物学] R737.33[医药卫生—肿瘤]