鼻咽癌调强放射治疗与常规放疗局部控制率的比较  

Comparison of local control rate with nasopharyngeal carcinoma intensity-modulated radiotherapy and conventional radiotherapy

作　　者：张福正[1] 车俊[1] 邹勤舟[1] 黄建锋[1] 范强[1] 楚建军[1] 赵的非[1] 贺蓓娃[1] 

机构地区：[1]苏州大学附属第四医院(无锡市第四人民医院),江苏无锡214062

出　　处：《中国当代医药》2012年第33期29-30,共2页China Modern Medicine

摘　　要：目的研究比较鼻咽癌常规放疗和调强放疗对鼻咽原发灶局部和颈部转移灶局部控制率的差异。方法用CMS放疗计划系统分别对30例T3N1M0鼻咽癌患者进行常规放疗和调强放疗计划设计,计算肿瘤量和正常组织照射剂量,观察2、3年局部控制率。结果调强放疗与常规放疗肿瘤所接受的剂量无显著差别,射野内正常组织受照剂量低于常规放疗,2、3年局部控制率调强放疗组分别为95%、93%,常规放疗组分别为83%、75%。结论鼻咽癌调强放疗与常规放疗相比,肿瘤靶区剂量精确可靠,调强放疗局部控制率优于常规放疗组,显示调强放疗具有更大的优越性。Objective To study and compare the local control rate of the primary location and lymph node metastasis for nasopharyngeal carcinoma between intensitymodulated radiation therapy （IMRT） and conventional radiation therapy （CRT）.Methods Thirty nasopharyngeal carcinoma patients in stage T3N1M0 planned with CMS system in IMRT and CRT,calculated the dose to tumor and normal tissues respectively.The 2-year and 3-year control rate was summarized.Results There was no significant difference about the dose to tumor between IMRT and CRT,but the dose to the normal tissuew was lower in IMRT than in CRT.The 2-year and 3-year control rate were 95%,93% with IMRT and 83%,75% with CRT.Conclusion The dose distribution to tumor target area is more creditable with IMRT than with CRT.The dose to the normal tissues is controlles effectively with IMRT,IMRT is more advantageous than CRT.

关 键 词：鼻咽癌 常规放疗 调强放疗 局部控制率 

分 类 号：R739.6[医药卫生—肿瘤]