癌症过度诊疗及其后果的研究进展  

The research progress of overdiagnosis and overtreatment in cancer

作　　者：徐骁盟(综述)[1] 韩晓冬(审校)[1] 

机构地区：[1]南京大学医学院免疫与生殖生物学实验室,江苏省医学分子技术重点实验室,南京210093

出　　处：《实用肿瘤学杂志》2012年第6期550-555,共6页Practical Oncology Journal

基　　金：国家自然科学基金（81170054）;江苏省自然科学基金（BK2011570）

摘　　要：癌症的筛查和早期诊断无疑对提高患者生存率、改善预后具有重大意义，但同时也会带来过度诊断和过度治疗，因为一部分癌症早期病灶即使不被诊断出来，也终生不产生临床症状，而诊断和治疗却会对患者造成医源性损伤，同时也会造成医疗资源的浪费。本文基于大量国内外最新文献，综述当今癌症过度医疗现状，分析其不良后果，并提出相关对策。Screening and early diagnosis of cancer, when making undoubted and significant contribution to the survival rate and clinical outcome of the disease, may lead to overdiagnosis and overtreatment because of the fact that some early stage cancers. Even if not detected,they are not going to cause any symptoms during the pa-tients＇ lifetime. But,the diagnosis and treatment would cause iatrogenic injury and a waste of medical resources. Based on large quantities of latest literatures worldwide, this article summarizes the ocurrent situation of cancer overdiagnosis, analyzes its adverse consequences and proposes several relevant solutions.

关 键 词：癌症 过度诊断 过度医疗 医源性损伤 

分 类 号：R73[医药卫生—肿瘤]