中国部分区域青少年早复极的检出率及随访  

Prevalence and prognostic value of early repolarization pattern in Chinese adolescent

作　　者：刘文玲[1] 周玉安 周广华[3] 李蕾[1] 张红[1] 张岚 赵杰强[3] 朱天刚[1] 赵博[1] 杨杰[1] 马占锋[4] 尹广利 

机构地区：[1]北京大学人民医院,北京100044 [2]北京市西城区中小学卫生保健所,北京100032 [3]北京大学医院,北京100871 [4]河北省沧州市中心医院,河北061001 [5]河北省沧州市中医院,河北061000

出　　处：《中国心脏起搏与心电生理杂志》2012年第6期498-500,共3页Chinese Journal of Cardiac Pacing and Electrophysiology

基　　金：首都医学发展科研基金(2009-2031);973计划(2007CB512103);北京大学人民医院研究与发展基金申请书RDC2011-18

摘　　要：目的了解中国青少年早复极(ER)的发生率及预后。方法 2008年9月至2010年10月,对北京市部分中学高一年级和职业中学新生、大学新入学的本科生进行筛查,包括询问病史及家族史,体格检查,心电图检查,必要时做超声心动图、动态心电图。并进行随访。ER诊断标准:心电图连续2个导联以上J点抬高至少0.1 mV,呈顿挫或切迹样,ST段呈凹面向上抬高,T波高尖。心电图由2名心内科医生阅图作出诊断。结果共获得了13405人有效心电图和相关资料,年龄15～22岁,男女比例1.01∶1。包括了我国34个省市自治区和特别行政区。涵盖了汉族、满族、蒙古族、苗族、藏族、朝鲜族和侗族,以汉族为主。共发现135例ER,男性111人,女性24人。检出率为1%。发生部位以下壁导联最多见,为79人;其次是下壁合并侧壁导联为29人。ER形态主要为顿挫型和切迹型。随访12～36个月,无1例发生心脏猝死等心血管事件,仅1例有黑矇,但未发现心律失常。结论初步显示ER在中国青少年中的发生率为1%,主要发生在下壁导联,其次是侧壁导联;总体上ER是一种良性表现。Objective To understand the prevalence and prognosis of early repolarization（ER） in Chinese adolescent. Method Students from some high schools and universities in Beijing were screened by ECG in 2008 -2010. Medical history, family history, and physical examination, including echocardiography, Hoher monitoring were recorded if necessa- ry. Students with ER had follow-up. Diagnostic criteria for ER： J-point elevation at least 0.1 mV and QRS notching or slurring more than 2 consecutive leads in 12-lead electrocardiography, ST segment elevation concave upward, high peak T- wave. ECG diagnosis were made by two experienced cardiologists. Results 13 405 valid ECG and related information were obtained, age 15-22 years old, male to female ratio 1.01： 1, including 34 provinces and autonomous regions and spe- cial administrative regions from China, Covering Han, Manzu, Mongolian, Miao, Tibetan, Korean, and Dong, mainly Han. Total of 135 cases of ER were found, male 111, female 24. The prevalence was 1%. They were mostly in inferior （79 cases） , next was both in inferior and lateral（ 29 cases） . The forms were mainly notching or slurring. Follow-up of 12- 36 months, no one had sudden cardiac death and other cardiovascular events, only 1 case had amaurosis, but no arrhythmi- as were recorded. Conclusion The prevalence of ER in Chinese adolescent is 1% based on this population, mainly ininferior and lateral leads; ER is generally benign.

关 键 词：心血管病学 早复极 心电图 青少年 

分 类 号：R540.41[医药卫生—心血管疾病] R339.31[医药卫生—内科学]