体外反搏对急性脑梗塞患者血浆ET、MDA及SOD作用的研究  

The Changes of Contents of Plasma ET、MDA and SOD in Patients with Acute Cerebral Infarction after External Conuterpulsation

作　　者：牛敬忠[1] 屈焕新[1] 朱文炳[2] 

机构地区：[1]泰山医学院附属医院,271000 [2]上海医科大学中山医院

出　　处：《山东医药》2000年第6期11-12,共2页Shandong Medical Journal

摘　　要：将 4 2例急性脑梗塞患者随机分为两组 ,对照组采用常规治疗 ,观察组在常规治疗基础上加用体外反搏 (ECP) ,分别于治疗前和治疗一个疗程后检测患者血浆内皮素 (ET)、丙二醛 (MDA)及超氧歧化酶 (SOD)含量。结果显示 ,两组患者治疗后血浆 ET、MDA含量下降 ,SOD含量升高 ,以观察组更加明显。血浆 ET与 MDA含量呈正相关 ,血浆 ET、MDA与 SOD含量呈负相关。认为 ECP能够降低急性脑梗塞患者血浆 ET含量 ,减轻脂质过氧化反应。WT5BZ]Fourty two acute cerebral infarction (ACI) patients were randomly divided into 2 groups The control group was treated with conventional therapeutics The observation group was treated with external counterpulsation (ECP) in addition to conventional therapeutics The contents of plasma ET、MDA and SOD were determined before and after treatment The result showed that the contents of the plasma ET and MDA were decreased and SOD contents were increased after treatment in two groups,especial in the observation group There were positive correlation between ET and MDA and negative correlation betwwen ET、MDA and SOD It suggested that ECP can reduce the contents of plasma ET and relieve lipid peroxidation reaction in ACI patients [WT5HZ]

关 键 词：体外反搏 内皮素 丙二醛 脑梗塞 SOD 

分 类 号：R743.33[医药卫生—神经病学与精神病学]