ELISA检测妇科肿瘤患者伴发弓形虫感染的调查  

DETECTION OF TOXOPLASMA INFECTION IN WOMEN WITH GYNAECOLOGIC NEOPLASMS USING ELISA 

作　　者：黄鹤[1] 阎福华[2] 李川江[1] 赵美毅[2] 汤俊文[2] 李向荣[2] 

机构地区：[1]湖北省医学科学院病毒研究所,武汉430079 [2]湖北省肿瘤医院妇科,武汉430079

出　　处：《中国寄生虫学与寄生虫病杂志》2000年第3期165-166,共2页Chinese Journal of Parasitology and Parasitic Diseases

摘　　要：[目的 ]了解妇科宫颈癌患者伴发弓形虫感染的情况。[方法 ]采用 EL ISA法检测弓形虫 Ig G、Ig M抗体和循环抗原。 [结果 ]宫颈癌、妇科良性肿瘤、其它疾患妇女 3组人群的弓形虫感染率分别为 :44 .0 % (2 2 / 5 0 )、2 5 .4% (15 / 5 9)和 2 0 .3% (2 8/ 138)。 3组人群 Ig G阳性率分别为 2 0 .0 0 %、11.86 %和 10 .87% ,Ig M阳性率分别为2 0 .0 0 %、13.5 6 %和 8.70 % ,循环抗原阳性率分别为 14.0 0 %、5 .0 9%和 1.45 %。 [结论 ]宫颈癌患者弓形虫感染率明显高于其它两组人群 ,以循环抗原和 IgObjective] To understand the concurrent in Toxoplasma infection among women with cervical cancer. [Methods] The anti Toxoplasma IgG, IgM antibodies (Abs) and circulating antigens (CAg) in 247 sera ( from 50 cases with cervical cancer in group 1, 59 cases with gynaecological benign tumors in group 2 and 138 cases with other diseases in group 3 ) were detected by ELISA. [Results] The total positive rates of the CAg and the Abs in the three groups were 44 0% (22/50), 25 4% (15/59) and 20 3% (28/138), respectively. The positive rates were 20 0%, 11 9% and 10 9%, respectively for IgG 20 0%, 13 6% and 8 7%, respectively fot IgM and 14 0%, 5 1% and 1 4% respectively for CAg. [Conclusion] The Toxoplasma infection rate of the cervical cancer group was higher than those of the other two groups, particularly the positive rates of CAg and IgM.

关 键 词：弓形虫感染 宫颈肿瘤 ELISA 循环抗原 

分 类 号：R737.304[医药卫生—肿瘤] R531.8[医药卫生—临床医学]