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机构地区:[1]广西医科大学第一附属医院皮肤性病科,广西南宁530021
出 处:《中国皮肤性病学杂志》2013年第1期61-63,共3页The Chinese Journal of Dermatovenereology
摘 要:患者男,60岁。全身结节、肿块十余年。左大腿结节组织病理示:真皮全层及皮下组织大量瘤细胞呈结节状密集分布,瘤细胞形态呈多形性,胞体大,核异型,可见较多多核巨细胞。免疫组化示:CD2,CD3和TIA-1均阳性,CD4,CD5及CD8均弱阳性,CD7,CD20,CD30,CD56,GrB及ALK均阴性,Ki-67显示高增殖指数(70%)。诊断:原发性皮肤外周T细胞淋巴瘤(非特殊类型)。A 60-year-old male had presented with nodules and tumors on the whole body for 10 years. The histopatho- L logic examination of a nodule from left thigh showed nodal infiltration of tumor cells in the dermis and subcu- taneous layer, with admixture of muhinucleated giant cells. The tumor cells have polymorphic form, big so- ma and abnormity nuclei. Immunohistochemistry study showed that CD2, CD3 and TIA-1 were positive, CIM, CD5 and CD8 were weak positive, CD7, CD20, CD30, CD56, GrB and ALK were negative, and Ki- 67 showed a high proliferation index (70%). The diagnosis of primary cutaneous peripheral T-cell lympho- ma, unspecified was made.
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