七叶洋地黄双苷滴眼液治疗青少年屈光不正性视疲劳  

Therapeutic effect analysis of esculin and digitalisglycosides eye drops on adolescent refractive asthenopia

作　　者：张庆[1] 石明华[1] 周伟[1] 龚淑贤[1] 

机构地区：[1]武汉爱尔眼科医院,中国湖北省武汉市430063

出　　处：《国际眼科杂志》2013年第1期137-138,共2页International Eye Science

摘　　要：目的:评价七叶洋地黄滴眼液治疗青少年屈光不正性视疲劳的效果。方法:研究对象为2011-04/2012-04在本院门诊就诊的屈光不正且具有典型的视疲劳症状患者200例400眼,年龄6～18岁,入选者采用(德国施图伦大药厂)七叶洋地黄双苷滴眼液3次/d,每次1滴,共使用1mo。通过进行调查问卷评分测定视疲劳主觉症状改善情况,以及视力和屈光度的改变和药物的不良反应。结果:用药前后患者的视疲劳主觉症状评分:治疗前3.67,治疗结束后1.89,治疗前和治疗后差异有统计学意义(P<0.05)。患者的裸眼视力有所提高,治疗前200例400眼平均视力为4.43±0.38,治疗后为4.60±0.49,组间比较差异有统计学意义(t=-3.87,P<0.05)。治疗前后屈光度由-2.54±3.00D降至-2.25±2.98D,但差异没有统计学意义(t=-0.96,P=0.33)。没有发现明显的不良反应。结论:七叶洋地黄滴眼液对青少年屈光不正性视疲劳安全、有效。AIM：To evaluate the curative effect of esculin and digitalisglycosides eye drops on adolescent refractive asthenopia.METHODS：Objects of study were patients with refractive asthenopia during April 2011 to April 2012,age from 6 to 18,totally 200 patients 400 eyes with typical visual fatigue symptoms were included.The enrolled patients used esculin and digitalisglycosides eye drops made by Germany,1 drop per time,t.i.d.duration of the treatment lasted for 1 month.The improvement of treatment including visual fatigue,vision,dioptric change and drug adverse reactions were determined by conducting questionnaires rating.RESULTS：Visual fatigue grade increased from 3.67 to 1.89 after the treatment,which had statistical significance（P0.05）.The naked eyesight of the patients improved from 4.43±0.38 to 4.60±0.49.Comparison differences between groups had statistical significance（t=-3.87,P0.05）.Dioptry decreased from-2.54±3.00D to-2.25±2.98D,but the differences had no statistical significance.There＇s no report for adverse reactions.CONCLUSION：Esculin and digitalisglycosides eye drops is safe and effective in treating adolescent refractive asthenopia.

关 键 词：近视 视疲劳 七叶洋地黄双苷 

分 类 号：R778.1[医药卫生—眼科]