用cDNA表达阵谱分析小鼠鼻咽部相对特异表达基因  

Analysis of the Gene Expression in Murine Nasopharyn by Mouse Atlas^(TM) cDNA Expression Array .

作　　者：张玲[1] 凌建华[1] 何志巍[1] 姚开泰[1] 

机构地区：[1]湖南医科大学肿瘤研究所,卫生部癌变重点实验室,长沙410078

出　　处：《生物化学与生物物理进展》2000年第1期86-90,共5页Progress In Biochemistry and Biophysics

基　　金：国家自然科学基金!重点项目 (39730 2 0 0 );美国中华医学会基金!(96 655)

摘　　要：利用MouseAtlasTMcDNAexpressionarray检测鼻咽、气管、食管、膀胱四种组织中588个已知基因的表达谱,得到11个在鼻咽上皮中表达相对较高的基因,作为鼻咽部组织相对特异基因的候选者,并用RTPCR进一步验证.genes expressed in nasopharynx, trachea , esophagus and bladder tissues were examined by Mouse Atlas TM cDNA expression array and there are 11 genes expressed much higher in nasopharynx than in other tissues .These genes might be candidates for relative tissue specific genes of nasopharynx. The expression result was further confirmed by RT PCR examination.

关 键 词：基因表达谱 鼻咽癌 特异表达基因 动物模型 

分 类 号：R739.63[医药卫生—肿瘤] Q75[医药卫生—临床医学]