代谢网络的重构  

Reconstruction of Metabolic Networks

作　　者：邓世果[1] 吴干华[1,2] 杨会杰[1] 

机构地区：[1]上海理工大学管理学院,上海200090 [2]华南师范大学南海学院,佛山528225

出　　处：《上海理工大学学报》2012年第6期511-516,共6页Journal of University of Shanghai For Science and Technology

基　　金：国家自然科学基金资助项目(10975099;10635040);上海市重点学科建设资助项目(S30501)

摘　　要：在已有的构建代谢网络方法的基础上,提出了构造代谢网络的改进方法.以鱼腥藻作为实例,利用KEGG数据库中生物体的生化反应、酶、基因数据重构出鱼腥藻的初步代谢网络,并对初步代谢网络进行了修正,讨论了该网络的拓扑结构性质.A new method was proposed to reconstruct metabolic networks on the basis of the existing method. As an illustration example, the method was used to build the metabolic network for a species of anabaena. By use of the data of organism＇s biochemical reaction, enzyme and gene in the Kyoto Encyclopedia of Genes and Genomes （KEGG） database, the preliminary metabolic network for the anabaena was reconstructed. The structural behaviors such as degree distribution, hierar chy,and community were discussed.

关 键 词：KEGG数据库 代谢网络 度分布 

分 类 号：N941[自然科学总论—系统科学]