黏附分子与痰邪致病相关性的探讨  

Discussion on Relevance Between Adhesion Molecules and Diseases Induced by Phlegm

作　　者：许湘[1] 王平[1] 汤琪[1] 蔡晓鸿[1] 

机构地区：[1]湖北中医药大学老年医学研究所国家中药管理局内经学重点学科,湖北武汉430065

出　　处：《辽宁中医杂志》2013年第1期57-59,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金重点项目(81130064)

摘　　要：痰邪是具有中医特色的病因之一,包括有形之痰和无形之痰,常与脑血管意外、冠心病、糖尿病、肿瘤等疾病的发生和发展密切相关。大量的临床、实验研究表明黏附分子与痰邪所致疾病有一定的相关性。故文章从黏附分子的作用特点,代谢、表达等方面与痰邪致病的相关性进行了探讨,推测黏附分子可能是痰邪致病的微观指标之一。这将有利于将中医理论中"痰"这一相对抽象概念具体化,拓展其实质内涵;为实验动物模型的筛选与建立等提供新的思路和契入点;为中医临床的"异病同治"提供一定的理论依据;为研发中药新药,提供新的作用靶点。The phlegm evil has Chinese characteristics, including visible phlegm and invisible phlegm, often associated with cerebral vascular accident, is closely related to the occurrence and development of coronary heart disease, diabetes, cancer and other diseases. A large number of clinical and laboratory studies have shown that adhesion molecules and diseases caused by phlegm evil have a certain correlation. So this article discusses the relevance between adhesion molecules and diseases induced by phlegm evil from the action characteristics, the metabolism, expression and other aspects of adhesion molecules. Then it speculates that adhesion molecules may be one of the microcosmic index of diseases induced by phlegm evil. This will help to abstract con- cept of phlegm in Traditional Chinese Medicine theory, and to expand its real connotation, providing new ideas and the contact point for the screening and the establishment of experimental animal models;providing a theoretical basis for the theory of same treatment for different diseases and providing new targets of new drugs development of Chinese medicine.

关 键 词：黏附分子 痰邪 致病机理 

分 类 号：R22[医药卫生—中医基础理论]