苏合香与安息香中挥发油成分的对比分析  

Comparative Analysis of Volatile Oil Components in Liquidambar orientalis and Styrax tonkinensis

作　　者：彭颖[1] 夏厚林[1] 周颖[1] 王建[1] 吴强[1] 郭帅[1] 贾芳[1] 

机构地区：[1]成都中医药大学,成都611137

出　　处：《中国药房》2013年第3期241-243,共3页China Pharmacy

基　　金：国家"973"重点基础研究发展规划项目资助(No.2007CB512606)

摘　　要：目的:对苏合香与安息香中挥发油成分进行对比分析。方法:采用水蒸气蒸馏法提取苏合香和安息香挥发油,以气相色谱-质谱(GC-MS)联用技术对挥发油中化学成分进行鉴定分析。色谱柱为19091N-133HP-INNO Wax(30m×0.25mm×0.25μm),进样口温度为250℃,采用程序升温条件,载气为高纯氦气,载气流量为1.0ml/min,分流比为10:1,电离方式为电轰击电离,电离能量为70eV,离子源温度为230℃,四极杆温度为150℃,传输线温度为150℃,质量扫描范围为20～450amu。结果:鉴定出苏合香挥发油中的42种成分,占总色谱峰面积的91%以上;鉴定出安息香挥发油中的19种成分,占总色谱峰面积的97%以上。2种挥发油中有异龙脑、合成右旋龙脑、苯甲醛、樟脑4种相同化学成分。结论:本试验结果可为进一步研究芳香开窍药的药效物质基础提供依据。OBJECTIVE：To analyze the volatile oil component from Liquidambar orientalis and Styrax tonkinensis.METHODS：The volatile oil was extracted from L.orientalis and S.tonkinensis by SD method and the chemical components of volatile oil were analyzed by GC-MS.The determination was performed on 19091N-133HP-INNO Wax（30 m×0.25 mm×0.25 μm）column,and the temperature of injector was 250 ℃,by temperature programming.Pure helium was used as carrier gas at flow rate of 1.0 ml/min with split ratio of 10：1.EI ionization mode was adopted,ionization energy was 70 eV and ion source temperature was 230 ℃.The temperature of quadrupoles and transmission lines both were 150 ℃ and mass scaning range were 20-450 amu.RESULTS：42 compounds were identified,which represented 91% of the total volatile oil from L.orientalis.19 compounds were identified,which represented 97% of the total volatile oil from S.tonkinensis.2 kinds of volatile oil contained same chemical components,such as isoborneol,d-borneol,benzaldehyde and camphor.CONCLUSION：Results of trial can provide reference for further study of pharmacodynamic material basis of aromatic drugs for inducing resuscitation.

关 键 词：苏合香 安息香 挥发油 气相色谱-质谱联用技术 成分分析 芳香开窍药 

分 类 号：R284.1[医药卫生—中药学] R917[医药卫生—中医学]