大分割适形放射治疗非小细胞肺癌12例疗效观察  

Observation of curative effect of hypo-fractionated conformal radiotherapy for 12 patients with non-small cell lung cancer

作　　者：罗树春[1] 兰海涛[1] 吴琦[1] 

机构地区：[1]四川省医学科学院.四川省人民医院肿瘤科,四川成都610072

出　　处：《实用医院临床杂志》2013年第1期125-126,共2页Practical Journal of Clinical Medicine

摘　　要：目的观察大分割适形放射治疗非小细胞肺癌的疗效和毒副反应。方法对12例非小细胞肺癌采用三维适形放疗,6 GY/次,5次/周,共60 GY/10次。结果近期疗效:完全缓解(CR)3例占25.0%,部分缓解(PR)5例占41.7%,稳定(SD)和疾病进展(PD)各2例,肿瘤客观缓解率(CR+PR)为66.7%,局部控制率(CR+PR+SD)83.3%。放射性肺炎0级8例、Ⅰ级3例、Ⅱ级1例;放射性食道炎0级9例、Ⅰ级2例、Ⅲ级1例。结论大分割适形放射治疗非小细胞肺癌近期疗效较好,副反应未明显增加。Objective To analyze the efficacy and complications of hypo-fractionated conformal radiotherapy for non-small cell lung cancer. Methods Twelve patients with non-small cell lung cancer were treated with hypo-fraction conformal radiotherapy. A dose of 60 GY was given in 10 fractions,once a day,and 5 fractions a week. Results The short-term results showed that the complete response（CR） rate, the partial response （PR）rate, the overall response （CR＋PR）rate and the local regional control rate （CR＋PR＋SD） were 25. 0% ,41.7% ,66. 7% and 83.3% ,respectively. There patients suffered from radiation penumonitis of grade I ,one patient had radiation penumonitis of grade II , and no patient developed serious（ grade III ）radiation penumonitis. Two cases suffered from radiation esophagitis of grade I , and one patient had radiation esophagitis of grade III. Conclusions The hypo-fraction conformal radiotherapy may be good for non-small cell lung cancer without incensement of complications.

关 键 词：非小细胞肺癌 放射治疗 

分 类 号：R734.2[医药卫生—肿瘤] R815[医药卫生—临床医学]