上海市医疗机构基因临床研究与应用的现状分析  

Study on Clinical Genetic Trials and Practice in Medical Institutions in Shanghai

作　　者：范竹萍[1] 白洁[2] 周萍[2] 达庆东[2] 薛迪[2] 纪洁[2] 

机构地区：[1]上海交通大学医学院附属仁济医院,上海200001 [2]复旦大学公共卫生学院,上海200032

出　　处：《中国医院管理》2013年第1期23-25,共3页Chinese Hospital Management

摘　　要：目的分析上海市基因临床研究与应用中存在或可能存在的伦理问题。方法对上海市22所医疗机构进行问卷调查,并对相关人员进行关键知情者访谈。结果被调查的上海市医疗机构中有7所开展基因工作,2011年公立医院基因检测平均服务量比2009年增长1.75倍;31%的公立医院从事基因工作的人员在近1年内参加过伦理培训,体检机构未向员工提供伦理培训;3所开展基因检测的机构未要求签署知情同意书。结论上海市基因临床研究与应用发展较快但应用不广,应进一步促进基因检测技术的临床应用,完善基因临床应用的伦理规范。Objective To analyze existing or potential ethical issues in clinical genetic trials and practice. Method A questionnaire survey of 22 medical institutions in Shanghai and key informant interviews were conducted. Results 7 medi- cal institutions had clinical genetic trials or services; the average number of genetic tests provided by public hospitals in 2011 was 1.75 times as high as that in 2009; 31% persons who worked on clinical genetic trials and/or services in the public hospitals had ethics training in the past year and no health examination institutions provided ethics training to their employees; and 3 institutions conducting clinical genetic testing did not require informed consent before providing them. Conclusion Clinical genetic trials and practice have developed rapidly in recent years but are still not widely used in Shang- hai. Genetic testing should be promoted to appty in clinics, and their application should be regulated according to ethical norms and criteria.

关 键 词：医疗机构 基因检测 基因治疗 生命伦理 

分 类 号：R197.3[医药卫生—卫生事业管理]