新型防污剂辣素衍生物的合成、抑菌性及防污性能研究  

Synthesis of Acrylamides Containing Capsaicin Derivative and Their Bacteriostatic Activity and Antifouling Capability

作　　者：闫雪峰[1] 于良民[1] 姜晓辉[1] 

机构地区：[1]中国海洋大学海洋化学理论与工程技术教育部重点实验室,山东青岛266100

出　　处：《中国海洋大学学报（自然科学版）》2013年第1期64-67,共4页Periodical of Ocean University of China

基　　金：国家高技术研究发展计划项目(2010AA09Z203;010AA065104);海洋公益性行业科研专项经费(201005028-2);青岛市公共领域科技支撑计划项目(11-2-3-34-nsh);长江学者奖励计划项目资助

摘　　要：合成了3种新型含辣素衍生结构的丙烯酰胺衍生物HMOBA、BMA和HMMBA,通过红外光谱(IR)和核磁波谱(1 HNMR)对其结构进行了表征。抑菌性实验证明了合成的化合物对金黄色葡萄球菌和大肠杆菌均有良好的抑制作用,抑菌效果为BMA>HMOBA>HMMBA,其中BMA的对两种菌的最小抑菌浓度均可达0.062 5mg/mL。以合成的化合物为防污剂制备了海洋防污涂料,186d的实海挂板几乎没有附着任何海洋污损生物。Three acrylamide compounds （HMOBA, BMA, HMMBA）, derived from capsaicin were synthesized and their structures were confirmed by IR spectroscopy and 1H NMR. The results showed that all the three compounds possessed good antibacterial activities, with MIC value of BMA to Escherichia Coli and Staphylococcus aureus reached 0. 062 5 mg/ml. These compounds were also studied as an antifouling agent in antifouling paint, and test panels immersed for 186 days was almost free of marine organisms.

关 键 词：含辣素的丙烯酰胺衍生物 抑菌活性 防污性能中图法 

分 类 号：TQ464.71[化学工程—制药化工] P755.3[天文地球—海洋科学]