磁刺激健康人咬肌抑制反射及恢复观察  

The masseter inhibitory reflex and the recovery of the reflex after magnetic stimulation in normal subjects

作　　者：黄黄[1] 宋宇涵[1] 王继军[2] 郭茜[2] 刘伟才[1] 

机构地区：[1]同济大学口腔医学院修复科,上海200072 [2]上海交通大学医学院附属精神卫生中心

出　　处：《中华口腔医学杂志》2013年第1期50-52,共3页Chinese Journal of Stomatology

基　　金：国家自然科学基金（30700960）;上海市科学技术委员会科研计划（10QAl407400）

摘　　要：目的研究磁刺激下健康人咬肌抑制反射（masseterinh ibitory reflex，MIR）及其恢复情况，为临床辅助检测颅面部疾病提供依据。方法选择30名健康人，单脉冲模式磁刺激颏神经，记录咬肌肌电，统计早期静息期（the early silent period，SPl）和晚期静息期（thelate silent period，SP2）的潜伏期及持续时间、SP2相对波幅值；在双脉冲模式的条件刺激和测试刺激间设置不同间隔时间（100、200、300、400、500和600ms），分析双脉冲模式磁刺激下MIR的恢复情况。结果健康人SPl潜伏期为12．1（11．1，14．4）ms，持续时间为（17．3±2．9）ms；SP2潜伏期和持续时间分别为（47．7±6．0）和（39．7±13．3）ms；SP2相对波幅值为100．0％。不同间隔双脉冲模式下测试刺激所得SPl有稳定的波段；而SP2发生变化，在间隔时间较短时测试刺激所得SP2的面积减少，随着间隔时间的延长，测试刺激所得SP2面积逐渐恢复，100ms时SP2面积恢复17．1％，400ms时恢复93．4％，600ms时几乎完全恢复。结论采用单脉冲和双脉冲模式磁刺激激发MIR并分析其恢复情况，可用来评估边缘系统、脑干、三叉神经感觉和运动纤维、咀嚼肌等整个系统的功能状态。Objective To analyze the masseter inhibitory reflex （MIR） and the recovery cycle of the MIR reflex after magnetic stimulation in normal subjects. Methods In 30 healthy subjects we studied the MIR evoked by single magnetic stimulation in the mental territory. Masseter electromyographic activity, latency and duration of the early silent periods （ SP1 ） and late silent periods （ SP2）, and SP2 amplitude percent were recorded. Paired stimuli technique was used, conditioning and test stimuli were delivered at different interstimulus intervals （ISI）, ie. 100,200,300,400,500, and 600 ms, then the recovery cycle of the MIR was analyzed. Results Latency of SP1 was 12. 1 （ 11.1,14. 4） ms, and duration of the SP1 was （ 17.3 ± 2.9） ms. Latency of SP2 was （47.7 ±6.0） ms, and duration of the SP2 was （39.7 ±13.3） ms. SP2 amplitude percent was 100. 0%. With the paired stimuli technique, sP1 of the inhibitory reflex evoked by the test stimuli was found to be stable at every ISis, but SP2 of the inhibitory reflex evoked by the test stimuli, instead, varied according to different ISI. With the short ISI, the area of SP2 evoked by the test stimuli was reduced, and with the increase of the ISI, the recovery degree of the area of SP2 evoked by the test stimuli was ascending, at 100 ms the SP2 amplitude percent was 17. 1%, at 400 ms it was 93.4%, and it was close to 100 % at 600 ms. Conclusions The study indicates that the use of the MIR elicited by the single and paired magnetic stimulation may be useful to examine or quantify some craniofacial diseases.

关 键 词：咬肌 反射 磁刺激 静息期 

分 类 号：R78[医药卫生—口腔医学]