胶体金法检测幽门螺杆菌的临床价值  

The Clinical Value of Dot Immunogold Filtration Assay in Testing Helicobacter Pylori Infection

作　　者：房晓芬[1] 朱志超[2] 

机构地区：[1]山西医科大学第一医院消化科,山西太原030001 [2]北京市通州区潞河医院消化科

出　　处：《中南医学科学杂志》2013年第1期58-60,共3页Medical Science Journal of Central South China

摘　　要：目的探讨胶体金法检测幽门螺杆菌感染的临床价值。方法门诊收集153例有上消化道症状的成年患者,均行13C呼气试验、胶体金法和快速尿素酶试验3种方法检查幽门螺杆菌,以13C呼气试验结果为"金标准",余两种检测方法分别与"金标准"进行比较。结果血清胶体金法可靠性较好,优于快速尿素酶法。结论胶体金法检测血清中幽门螺杆菌抗体,有较高的准确率及特异性,取材方便,操作简便,是较为理想的检测幽门螺杆菌感染的方法。Objective To investigate the Dot hnmunogold Filtration Assay （DI-GFA） in testing Helicobacter pylori （H. pylori ） infection. Method 153 outpatients with upper gastrointestinal symptoms were selected, who were detected by 13 C-Urea Breath Test and Dot Immunogold Filtration Assay and Rapid Urease Test. serologic testing. 13 C-UBT was used as the ＂gold standard＂, and the others were compared with the ＂＇ gold standard＂. Results Dot Immunogold Filtration As- say was more reliable and superior than Rapid Urease Test. Conclusion Dot Immunogold Filtration Assay has higher ac- curac.y and specificity in detecting helicobacter pylori antibody, with convenient materials and simple operation, which is a kind of ideal method for detecting Helicobacter pylori.

关 键 词：幽门螺杆菌 胶体金法 13C呼气试验 快速尿素酶试验 

分 类 号：R573.6[医药卫生—消化系统]