聚乙烯醇(PVA)水凝胶的制备  

Study on preparation and performance of PVA hydrogel

作　　者：胡孝丽[1] 冷卫东[1] 陈士龙[2] 杨燕[1] 周娟[1] 

机构地区：[1]湖北医药学院附属太和医院口腔科,湖北十堰442000 [2]湖北医药学院附属人民医院口腔科,湖北十堰442000

出　　处：《临床口腔医学杂志》2013年第1期23-25,共3页Journal of Clinical Stomatology

基　　金：云南省教育厅基金项目(4209060)

摘　　要：目的:制备聚乙烯醇水凝胶,并对影响水凝胶含水率的各种因素进行探索,为其应用于口腔软组织增量提供实验依据。方法:利用冷冻解冻法对PVA水溶液进行物理交联制备PVA水凝胶;正态性检验和方差齐性检验研究PVA分子量、冷冻循环次数以及PVA浓度对凝胶含水率的影响。结果:PVA分子量、冷冻循环次数及PVA浓度对凝胶含水率均有影响,差异有显著性(P<0.05)。结论:高浓度高分子量PVA水凝胶经3～7次冷冻循环后具有高含水率,可以考虑将其应用于口腔软组织增量。Objective：The preparation of polyvinyl alcohol（PVA） hydrogel experiment to study cytotoxicity of water-swelling properties of the gel.for its application in the oral soft tissue incremental provide experimental basis.Method：By freezing and thawing method of physical crosslinking of the PVA solution,Test of normality and F test research PVA molecular weight,refrigeration cycle times and PVA gel concentration on the influence of moisture content.Result：PVA molecular weight,refrigeration cycle times and concentration of PVA gel all affect the moisture content,their difference was significant（P 0.05）.Conclusion：PVA hydrogel has a high moisture content by 3～7 times the refrigeration cycle,and then its increment can apply to the oral soft tissues to provide experimental basis.

关 键 词：聚乙烯醇 水凝胶 含水率 

分 类 号：R783.1[医药卫生—口腔医学]