内生场热疗联合糖皮质激素治疗急性放射性肺炎的疗效观察  

Efficacy of local endogenefic thermotherapy combined with glucocorticoid for acute radiation pneumonia

作　　者：黄建国[1] 卢宁[1] 王勇强[1] 赵晓伟[1] 

机构地区：[1]兰州军区乌鲁木齐总医院肿瘤科,新疆乌鲁木齐830000

出　　处：《现代肿瘤医学》2013年第2期340-342,共3页Journal of Modern Oncology

摘　　要：目的:观察内生场热疗联合糖皮质激素治疗放射性肺炎的临床疗效。方法:86例放射性肺炎患者随机分为4组,分别给予对应治疗后,根据治疗后的症状、体征和影像学检查结果判定疗效。结果:内生场热疗和地塞米松联合治疗组患者,咳嗽、咳痰、胸闷气促症状以及呼吸困难症状有明显改善或消失,胸部CT提示肺部炎症消失或减轻,显效10例,有效10例,有效率90.9%,与治疗前相比均具有显著统计学差异(P<0.01)。糖皮质激素组及热疗组患者经治疗后症状均有一定改善,其中糖皮质激素组显效5例,有效10例,有效率68.2%;热疗组显效6例,有效8例,有效率63.6%。对照组患者显效1例,有效3例,有效率25%。3个治疗组有效率均显著高于对照组(P<0.01),联合治疗组有效率显著高于糖皮质激素组(P<0.05)及热疗组(P<0.05)。结论:内生场热疗联合糖皮质激素治疗放射性肺炎,疗效显著,值得临床推广应用。Objective：To observe the clinical efficacy of local endogenefic thermotherapy combined with glucocorticoids for acute radiation pneumonia. Methods： All 86 cases of radiation pneumonitis were randomly divided into four groups and given the corresponding treatment. After treatment, the efficacy was determined according the symptoms, signs and imaging findings. Results： The patients treated with local endogenefic thermotherapy combined with glucocorticoids, symptoms including cough, sputum, chest tightness, shortness of breath and dyspnea were significantly improved or disappeared and lung inflammation was disappeared or reduced shown by chest CT. The excellent effective and effective cases both were 10 respectively and the effective rate was 90.9% （ P 〈 0.01, compared with before treatment）. Patients＇ symptoms treated with glucocorticoid and hyperthermia have improved to some extent. The excellent effective and effective cases were 5 and 10 respectively and the effective rate was 68.2% in glucocorticoid group. The results were 6 and 8 cases and 63.6% in local endogenefic thermotherapy group. In control group,the excellence and effective cases were 1 and 3 cases respectively and the effective rate was only 20%. The effective rates of the three treatment groups were significantly higher than the control group （P 〈 0.01 ）. The effective rate of combination therapy group was significantly higher than the glucocorticoid group （P 〈 0.05） and local endogenefic thermotherapy groups （P 〈 0.05）. Conclusion： The clinical efficacy of local endogenefic thermotherapy combined with glucocorticoid for acute radiation pneumonia was effective and worthy of clinical application.

关 键 词：内生场热疗 糖皮质激素 放射性肺炎 治疗 

分 类 号：R734.2[医药卫生—肿瘤]