库肯勃氏瘤预后相关因素分析  

The Prognosis Factors of Krukenburg Tumor

作　　者：李梅 彭素蓉[2] 陈小祥[2] 陈环球[2] 

机构地区：[1]荆门市第二人民医院妇产科,448000 [2]南京医科大学附属江苏省肿瘤医院,210009

出　　处：《实用癌症杂志》2013年第1期80-83,共4页The Practical Journal of Cancer

摘　　要：目的分析库肯勃氏瘤的临床病理特征、治疗方式及预后相关性。方法对56例库肯勃氏瘤的预后因素进行回顾性分析,应用COX风险比例模型分析预后相关因素,采用Kaplan-Meier法评估相关因素对患者生存期的影响。结果 56例患者平均生存期为11.2个月,转移部位(P=0.01)及手术方式(P=0.03)影响患者总生存时间;单纯卵巢转移者较合并其它部位转移者总生存期长(12.8 Vs 5.8月),原发肿瘤与卵巢转移性肿瘤同时切除者较单纯切除卵巢转移病灶者总生存期长(14.2 Vs 7.9月)。结论库肯勃氏瘤多发于年轻、绝经前女性患者。外科及妇科联合手术治疗可延长患者生存期。Objective To determine the prognosis factors including clinicopathological characteristics and therapy choices in Krukenburg tumor.Methods In this retrospective study,we identified 56 Krukenburg tumors between 1982 and 2009.A Cox proportional hazards model and log-rank test were used to assess associations between these factors and overall survival.Results The median overall survival duration of Krukenburg tumor was 11.2 months.The type of metastatic（P=0.01） and surgery（P=0.03） were related with overall survival.The overall survival durations of Krukenburg tumor without other metastatic lesions and those dissected of primary tumor synchronically were longer than those with other metastatic tumors（12.8 Vs 5.8 months） and didn＇t dissect primary tumor（14.2 Vs 7.9 months）.Conclusion Most of Krukenburg tumor patients are young,premenopausal women.Dissection of primary tumor and ovarian metastatic tumor synchronically will prolong survival duration of those cases.

关 键 词：库肯勃氏瘤 胃癌 结肠癌 直肠癌 预后 

分 类 号：R737.31[医药卫生—肿瘤]