长时间应用甘露醇致硬膜下积液三例  

Subdural hygromas caused by excess adminstration of mannitol:3 cases report

作　　者：陈盼虎[1] 孙国柱[1] 杨连琦[1] 马波涛[1] 朱小辉[1] 

机构地区：[1]河北医科大学第二医院神经外科,石家庄050000

出　　处：《脑与神经疾病杂志》2013年第1期39-41,共3页Journal of Brain and Nervous Diseases

基　　金：河北省自然基金资助项目(C2008001084);河北省医学科学重点课题(20090091;20120073)

摘　　要：目的对3例长时间应用甘露醇导致硬膜下积液的发生机制及治疗进行初步探讨。方法回顾性分析我院神经外科收治的因过度应用甘露醇出现硬膜下积液的3例颅脑损伤患者的临床资料,其中2例实行开颅手术,均应用甘露醇静点降颅压,半月后出现硬膜下积液。结果停用甘露醇后硬膜下积液不见好转,应用锥颅置管外引流术当时有效,拔除引流管后硬膜下积液又恢复原状,采用硬膜下积液腹腔分流术缓解。结论颅脑损伤后应用甘露醇时间太长易形成硬膜下积液,硬膜下积液腹腔分流术是治疗硬膜下积液的有效措施。Objective To report three cases of subdural hygromas caused by excess administation of mannitol and investigate their probable mechanism. Methods The patients enrolled in our study were all inpatients of cranial injury in our ht）spital, two of whiteh were performed craniotmny. All of cases developed subdural hygromas afler adminislrated excess use of mannitol half of monlh later. Results Sul）dural hygromas in 3 eases did not improve by discnntinuation of mannitnl and subdural external drainage only exerled temporary effect. Sylvian araehnoid ostomy or subdural peritoneal slunt dissolved subdural hygroas in all cases. Conclusion Excess adminstration of mannitol is prone In develop subdt, ral hygromas. Sylvian araehnoid ostomy or stiI）dnral peritoneal shunt is a saife and effeelive measure for st, bdural hygromas.

关 键 词：硬膜下积液 甘露醇 机制 手术治疗 

分 类 号：R741[医药卫生—神经病学与精神病学]